CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030964
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aldo-keto reductase family 1 member C3 
Protein Synonyms/Alias
 Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_c; cDNA FLJ57019, highly similar to Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) 
Gene Name
 AKR1C3 
Gene Synonyms/Alias
 hCG_19343 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
60QLEMILNKPGLKYKPubiquitination[1]
64ILNKPGLKYKPVCNQubiquitination[1]
66NKPGLKYKPVCNQVEubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 204 AA 
Protein Sequence
MSLKPGEELS PTDENGKVIF DIVDLCTTWE AMEKCKDAGL AKSIGVSNFN RRQLEMILNK 60
PGLKYKPVCN QVECHPYFNR SKLLDFCKSK DIVLVAYSAL GSQRDKRWVD PNSPVLLEDP 120
VLCALAKKHK RTPALIALRY QLQRGVVVLA KSYNEQRIRQ NVQVFEFQLT AEDMKAIDGL 180
DRNLHYFNSD SFASHPNYPY SDEY 204 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00062; ALDOKETO_REDUCTASE_2
 PS00063; ALDOKETO_REDUCTASE_3 
PRINTS
 PR00069; ALDKETRDTASE.