CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycerol kinase 
Protein Synonyms/Alias
 ATP:glycerol 3-phosphotransferase; Glycerokinase; GK 
Gene Name
 glpK 
Gene Synonyms/Alias
 BSU09290 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
90ETTVVWDKDTGSPVYacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
 Key enzyme in the regulation of glycerol uptake and metabolism. 
Sequence Annotation
 NP_BIND 410 414 ATP (By similarity).
 BINDING 12 12 Substrate (By similarity).
 BINDING 16 16 ATP (By similarity).
 BINDING 82 82 Substrate (By similarity).
 BINDING 134 134 Substrate (By similarity).
 BINDING 244 244 Substrate (By similarity).
 BINDING 266 266 ATP (By similarity).
 BINDING 309 309 ATP; via carbonyl oxygen (By similarity).
 MOD_RES 230 230 Phosphohistidine; by HPr (By similarity).  
Keyword
 ATP-binding; Complete proteome; Glycerol metabolism; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 496 AA 
Protein Sequence
METYILSLDQ GTTSSRAILF NKEGKIVHSA QKEFTQYFPH PGWVEHNANE IWGSVLAVIA 60
SVISESGISA SQIAGIGITN QRETTVVWDK DTGSPVYNAI VWQSRQTSGI CEELREKGYN 120
DKFREKTGLL IDPYFSGTKV KWILDNVEGA REKAEKGELL FGTIDTWLIW KMSGGKAHVT 180
DYSNASRTLM FNIYDLKWDD ELLDILGVPK SMLPEVKPSS HVYAETVDYH FFGKNIPIAG 240
AAGDQQSALF GQACFEEGMG KNTYGTGCFM LMNTGEKAIK SEHGLLTTIA WGIDGKVNYA 300
LEGSIFVAGS AIQWLRDGLR MFQDSSLSES YAEKVDSTDG VYVVPAFVGL GTPYWDSDVR 360
GSVFGLTRGT TKEHFIRATL ESLAYQTKDV LDAMEADSNI SLKTLRVDGG AVKNNFLMQF 420
QGDLLNVPVE RPEINETTAL GAAYLAGIAV GFWKDRSEIA NQWNLDKRFE PELEEEKRNE 480
LYKGWQKAVK AAMAFK 496 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
 GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP. 
Interpro
 IPR018485; Carb_kinase_FGGY_C.
 IPR018483; Carb_kinase_FGGY_CS.
 IPR018484; Carb_kinase_FGGY_N.
 IPR005999; Glycerol_kin. 
Pfam
 PF02782; FGGY_C
 PF00370; FGGY_N 
SMART
  
PROSITE
 PS00933; FGGY_KINASES_1
 PS00445; FGGY_KINASES_2 
PRINTS