CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039230
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myo5c 
Protein Synonyms/Alias
  
Gene Name
 Myo5c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
737QYQFGRTKIFFRAGQacetylation[1]
1037REEIKALKDERTQLHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1742 AA 
Protein Sequence
MAVAELYAQY NRVWIPDPEE VWKSAEIAKD YRVGDQVLRL LLEDGTELDY PVDPGSLPPL 60
RNPDILVGEN DLTALSYLHE PAVLHNLRIR FAESKLIYTY SGIILVAMNP YKQLPIYGDA 120
IIHAYSGQNM GDMDPHIFAV AEEAYKQMAR NNRNQSIIVS GESGAGKTVS ARYAMRYFAT 180
VSKSSSNAHV EEKVLASNPI TEAVGNAKTT RNDNSSRFGK YTEISFDERN QIIGANMRTY 240
LLEKSRVVFQ SENERNYHIF YQLCASAQQS EFKHLKLGSA EEFNYTRMGG NTVIEGVDDR 300
ADMAETQKTF TLLGFKKDFQ MDVFKILAAI LHLGNVQVTT VGNERSAVSE DDSHLKVFCE 360
LLGLETIKVA QWLCNRKIVT SSETVVKPMT RPQAINARDA LAKKIYAHLF DFIVEQINQA 420
LHFSGKQHTF IGVLDIYGFE TFDVNSFEQF CINYANEKLQ QQFNLHVFKL EQEEYMKEDI 480
PWTLIDFYDN QPVIDLIEAK MGILELLDEE CLLPHGTDEN WLQKLYNNFV NKNSLFEKPR 540
MSNSSFIIQH FADKVEYQCE GFLEKNRDTV YDMLVEVLRA SKFHLCAAFF QESPVPSSPF 600
GAMITVKSAK QVIKPNTKHF RTTVGNKFRS SLFLLMETLN ATTPHYVRCI KPNDEKLPFE 660
FDSKRIVQQL RACGVLETIR ISAQSYPSRW TYLEFYSRYG VLMTQQELSL SDKKEVCKVV 720
LHRLIQDSNQ YQFGRTKIFF RAGQVAYLEK LRLDKLRQGC IVIQKHVRGW LQRKKFLRER 780
RAALTIQQYF RGQQTVRKAI TATALKEAWA AIILQKHCRG YLVRNLYQLI RVATITIQAH 840
TRGFLARRRY RKLLQEHKAV ILQKYARAWL ARRRFQNIRR FVLNIQLTYR VQRLQKKLED 900
QNRENHGLVE KLTSLAALRV GDLEKVQRLE AELEKAATHR HSYEEKGRRY RDSMEERLSK 960
LQKHNAELES QRERAEQSLQ ERTEELKEKM DQLTRQLFDD VQKEEQQRLL LEKSFELKTQ 1020
AYEKEIESLR EEIKALKDER TQLHHQLEEG RVTSDSLKGE VARLSKQAKT ISEFEKEIEL 1080
LQAQKIDVEK HVQSQKREMR ERMSEVTKQL LESYDIEDVR SRLSVEDLEH LNEDGELWFA 1140
YEGLKKATRV LESHFQSQKD CYEKEIEGLN FKVVHLSQEI NHLQKLFREE TDINESIRHE 1200
VTRLTSENMM IPDFKQQISE LERQKQDLES RLKEQAEKME GKQEEPFSHL NRGLEEEGRQ 1260
GKAVEAQSET HPEGKERLVG KIQEPQEAIK FPKKQAEAEE EVESILRQEA SRLSLENRDL 1320
EEELDMKDRM IRKLQDQVKT LTRTIEKANS VPLPSGSREY LGMLEYKKED ETKLIQNLIL 1380
DLKPRGVVVN MIPGLPAHIL FMCVRYADSL NDANMLKSLM NSAINGIKHV VKEHFEDLEM 1440
LSFWLSNTCH FLNCLKQYSG EEEFMKCNSP QQNKNCLNNF DLTEYRQILS DVAIRIYHQF 1500
ILVMENNLQP IIVPGMLEYE SLQGISGLKP TGFRKRSSSI DDTDAYTMTS ILQQLSYFYS 1560
TMCQNGLDPE IVRQAVKQLF YLIGAVTLNS LLLRKDMCSC RKGMQIRCNI SFLEEWLKDK 1620
NLQNSLAKET LEPLSQAAWL LQVKKTTDSD AKEISQCCTS LSAVQIIKIL NSYTPIDDFE 1680
KRVNPSFVRK VQALLNNRGD SSQLMLDTKY LFQVTFPFTA SPHALEMTQI PSSFKLGFLR 1740
RL 1742 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR018444; Dil_domain.
 IPR002710; Dilute.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR001609; Myosin_head_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF01843; DIL
 PF00612; IQ
 PF00063; Myosin_head 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS51126; DILUTE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.