CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030280
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Occludin 
Protein Synonyms/Alias
 Occludin, isoform CRA_a; Ocln protein 
Gene Name
 Ocln 
Gene Synonyms/Alias
 mCG_116163 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
274RKMDRYDKSNILWDKubiquitination[1]
297PNVEEWVKNVSAGTQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Membrane; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 521 AA 
Protein Sequence
MSVRPFESPP PYRPDEFKPN HYAPSNDMYG GEMHVRPMLS QPAYSFYPED EILHFYKWTS 60
PPGVIRILSM LIIVMCIAIF ACVASTLAWD RGYGTGLFGG SLNYPYSGFG YGGGYGGGYG 120
GYGYGYGGYT DPRAAKGFLL AMAAFCFIAS LVIFVTSVIR SGMSRTRRYY LIVIIVSAIL 180
GIMVFIATIV YIMGVNPTAQ ASGSMYGSQI YMICNQFYTP GGTGLYVDQY LYHYCVVDPQ 240
EAIAIVLGFM IIVAFALIIF FAVKTRRKMD RYDKSNILWD KEHIYDEQPP NVEEWVKNVS 300
AGTQDMPPPP SDYAERVDSP MAYSSNGKVN GKRSYPESFY KSTPLVPEVA QEIPLTLSVD 360
DFRQPRYSSN GNLETPSKRA PTKGKAGKGK RTDPDHYETD YTTGGESCEE LEEDWVREYP 420
PITSDQQRQL YKRNFDAGLQ EYKSLQAELD DVNKELSRLD KELDDYREES EEYMAAADEY 480
NRLKQVKGSA DYKSKRNYCK QLKSKLSHIK RMVGDYDRRK P 521 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IDA:MGI.
 GO:0016327; C:apicolateral plasma membrane; IDA:MGI.
 GO:0009986; C:cell surface; ISO:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005923; C:tight junction; IDA:MGI.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0045216; P:cell-cell junction organization; IEA:Compara. 
Interpro
 IPR008253; Marvel.
 IPR021128; MARVEL-like_dom.
 IPR002958; Occludin.
 IPR010844; Occludin_RNApol2_elong_fac_ELL. 
Pfam
 PF01284; MARVEL
 PF07303; Occludin_ELL 
SMART
  
PROSITE
 PS51225; MARVEL 
PRINTS
 PR01258; OCCLUDIN.