CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037761
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 
Protein Synonyms/Alias
  
Gene Name
 MACF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
715LKAEPLTKATHSSSTubiquitination[1]
972LQDSIKRKYSCDHNTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1062 AA 
Protein Sequence
MGNSLGCFKE PKESIAIPEK APISPKKRVR FKRRWRGKKI PTPEASHQEE TSEGTGVIEE 60
TETLTKLTES LQKEDGVGGV EHTPPDILLP GDSAPNSRVV DRGMIVQVKE RFQGEVQTAH 120
LLLENESSVA GGVWDSLEEG MTVIAHLLDN PAERNCEKSV SQLVEFPRTA SCSSRAVLLP 180
LQGETAVEKG NIQRGFRSCA LPRTDYPTDK GNQEQFSEGW SVEEGTKSVS GAPQTASWII 240
ECSVSSLLLD QPGGQRRTEP SHVGQVPPQD SRLPTSQSDL SISGVTVSIL PSSSGYGSDG 300
PHIHGIQPKD TEPEKSSTSF SEEDGTLSLE ASHTPSWGLE EISDIYISGE SGDMSAKEKL 360
LLWTQKVTAG YTGIKCTNFS SCWSDGKMFN ALIHRYRPDL VDMERVQIQS NRENLEQAFE 420
VAERLGVTRL LDAEDVDVPS PDEKSVITYV SSIYDAFPKV PEGGEGISAT EVDSRWQEYQ 480
SRVDSLIPWI KQHTILMSDK TFPQNPVELK ALYNQYIHFK ETEILAKERE KGRIEELYKL 540
LEVWIEFGRI KLPQGYHPND VEEEWGKLII EMLEREKSLR PAVERLELLL QIANKIQNGA 600
LNCEEKLTLA KNTLQADAAH LESGQPVQCE SDVIMYIQEC EGLIRQLQVD LQILRDENYY 660
QLEELAFRVM RLQDELVTLR LECTNLYRKG HFTSLELVPP STLTTTHLKA EPLTKATHSS 720
STSWFRKPMT RAELVAISSS EDEGNLRFVY ELLSWVEEMQ MKLERAEWGN DLPSVELQLE 780
TQQHIHTSVE ELGSSVKEAR LYEGKMSQNF HTSYAETLGK LETQYCKLKE TSSFRMRHLQ 840
SLHKFVSRAT AELIWLNEKE EEELAYDWSD NNSNISAKRN YFSELTMELE EKQDVFRSLQ 900
DTAELLSLEN HPAKQTVEAY SAAVQSQLQW MKQLCLCVEQ HVKENTAYFQ FFSDARELES 960
FLRNLQDSIK RKYSCDHNTS LSRLEDLLQD SMAQDEKEQL IQSKSSVASL VGRSKTIVQL 1020
KPRSPDHVLK NTISVKAVCD YRQIEGRTIL SEGYGPLASA AC 1062 
Gene Ontology
  
Interpro
 IPR001715; CH-domain.
 IPR018159; Spectrin/alpha-actinin. 
Pfam
 PF00307; CH 
SMART
 SM00033; CH
 SM00150; SPEC 
PROSITE
 PS50021; CH 
PRINTS