CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035310
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear receptor co-repressor 2 (Predicted), isoform CRA_a 
Protein Synonyms/Alias
 Protein Ncor2 
Gene Name
 Ncor2 
Gene Synonyms/Alias
 Ncor2_predicted; rCG_21882 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
959RASTSPQKPLDLKQLacetylation[1]
1506VVVPELGKPRQSPLAacetylation[1]
1921AGHAFLTKPPAREPAacetylation[1]
1984HREKTQSKPFSIQELacetylation[1]
2028THDKGLSKPLEELEKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Receptor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2472 AA 
Protein Sequence
MSGSTQPVAQ TWRAAEPRYP PHGISYPVQI ARPHTDVGLL EYQHHPRDYT SHLSPGSIIQ 60
PQRRRPSLLS EFQPGSERSQ ELHLRPESRT FLPELGKPDI EFTESKRPRL ELLPDTLLRP 120
APLLATGQPS GSEDLTKDRS LAGKLEPVSP PSPPHADPEL ELTPSRLSKE ELIQNMDRVD 180
REITMVEQQI SKLKKKQQQL EEEAAKPPEP EKPVSPPPIE SKHRSLVQII YDENRKKAEA 240
AHRILEGLGP QVELPLYNQP SDTRQYHENI KINQAMRKKL ILYFKRRNHA RKQWEQRFCQ 300
RYDQLMEAWE KKVERIENNP RRRAKESKVR EYYEKQFPEI RKQRELQERM QSRVGQRGSG 360
LSMSAARSEH EVSEIIDGLS EQENLEKQMR QLAVIPPMLY DADQQRIKFI NMNGLMDDPM 420
KVYKDRQVTN MWSEQERDTF REKFMQHPKN FGLIASFLER KTVAECVLYY YLTKKNENYK 480
SLVRRSYRRR GKSQQQQQQQ QQQQQQQMAR SSQEEKEEKE KEKEADKEEE KQDAENEKEE 540
LSKEKTDDTS GEDNDEKEAV ASKGRKTANS QGRRKGRITR SMANEANHEE TATPQQSSEL 600
ASMEMNESSR WTEEEMETAK KGLLEHGRNW SAIARMVGSK TVSQCKNFYF NYKKRQNLDE 660
ILQQHKLKME KERNARRKKK KTPAAASEET AFPPAAEDEE MEASGASANE EELAEEAEAS 720
QASGNEVPRV GECSGPAAVN NSSDTESVPS PRTEATKDAG PKPASTEALP AATQPPVPPP 780
EEPATVPDEP CPAPDASGPP SPVASPPPAA PPAAVDKDEQ DQAATVPQTE DAKEQKSEAE 840
ELVIDVGKTE EPEAPEEPPE SVKSDHKEET EEEPEDKAKG PEAIETVSEA PLKVEEAGSK 900
AAVTKGSSSG ATQDSDSSAT CSADEVDEPE GGDKGRLLSP RPSLLTPAGD PRASTSPQKP 960
LDLKQLKQRA AAIPPIVTKV HEPPREDTVP PKPAPPVPPP TQHLQPEGDV SQQSGGSPRG 1020
KCRSPVPPAE KEAEKASFFP AFPAEGPKLP TEPPRWTSGL PFPIPPREVI KTSPHAADPS 1080
AFSYTPPGHP LPLGLHDSAR PVLPRPPISN PPPLISSAKH PGVLERQLGT ISQQGMSVQL 1140
RVPHSEHAKA PMGPLTMGLP LAVDPKKLGT ALGSTASGSI TKGLPSTRTA DGPSYRGSIT 1200
HGTPADVLYK GTISRIVGED SPSRLDRARE DTLPKGHVIY EGKKGHVLSY EGGMSVSQCS 1260
KEDGRSSSGP PHETAAPKRT YDMMEGRVGR TITSASIEGL MGRAIPEQHS PHLKEQHHIR 1320
GSITQGIPRS YVEAQEDYLR REAKLLKREG TPPPPPPPRD LTETYKTRPL DPLGPLKLKP 1380
THEGVVATVK EAGRSIHEIP REELRRTPEL PLAPRPLKEG SITQGTPLKY DSGVPSSGSK 1440
KHDVRSIIGS PGRPFPALHP LDIMADARAL ERACYEESLK SRSGTSSGAG GSITRGAPVV 1500
VPELGKPRQS PLAYEDHGAP FTSHLPRGSP VTTREPTPRL QEGSLLSSKA SQDRKLTSTP 1560
REIAKSPHST VPEHHPHPIS PYEHLLRGVT GVDLYRGHIP LAFDPTSIPR GIPLEAAAAA 1620
YYLPRHLAPS PTYPHLYPPY LIRGYPDTAA LENRQTIIND YITSQQMHHN AASAMAQRAD 1680
MLRGLSPRES SLALNYAAGP RGIIDLSQVP HLPVLVPPTP GTPATAIDRL AYLPTAPPPF 1740
SSRHSSSPLS PGGPTHLAKP TATSSSERER ERERERDKSI LTSTTTVEHA PIWRPGTEQS 1800
SGAGGSSRPA SHTHQHSPIS PRTQDALQQR PSVLHNTSMK GVVTSVEPGT PTVLRWARST 1860
STSSPVRPAA TFPPATHCPL GGTLEGVYPT LMEPVLLPKE TSRVTRPERP RVDAGHAFLT 1920
KPPAREPASS PSKSSEPRSL APPSSSHTAI ARTPAKSLAP HHASPDLPAP TSASDLHREK 1980
TQSKPFSIQE LELRSLGYHS GAGYSPDGVE PISPVSSPSL THDKGLSKPL EELEKSHLEG 2040
ELRHKQPGPM KLSGEAAHLP HLRPLPESQP SSSPLLQTAP GIKGHQRVVT LAQHISEVIT 2100
QDYTRHHPQQ LSGPLPAPLY SFPGASCPVL DLRRPPSDLY LPPPDHGTPA RGSPHSEGGK 2160
RSPEPSKTVL SSSEDAIEPV SPPEGMTEPG HARSTAYPLL YRDGEQGEPR MGSKSPGNTS 2220
QPPAFFSKLT ESNSAMVKSK KQEINKKLNT HNRNEPEYNI GQPGTEIFNM PAITGAGLMT 2280
CRSQAVQEHA STNMGLEAII RKALMGKYDQ WEEPPPLGAN AFNPLNASAS LPAAAMPITT 2340
ADGRSDHPLT SPGGGGKAKV SGRPSSRKAK SPAPGLAPGD RPPSVSSVHS EGDCNRRTPL 2400
TNRVWEDRPS SAGSTPFPYN PLIMRLQAGV MASPPPPGLA AGSGPLAGPH HAWDEEPKPL 2460
LCSQYETLSD SE 2472 
Gene Ontology
 GO:0000785; C:chromatin; IDA:RGD.
 GO:0000118; C:histone deacetylase complex; IEA:Compara.
 GO:0016604; C:nuclear body; IEA:Compara.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0003682; F:chromatin binding; IDA:RGD.
 GO:0001012; F:RNA polymerase II regulatory region DNA binding; IDA:RGD.
 GO:0043565; F:sequence-specific DNA binding; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0021846; P:cell proliferation in forebrain; IEA:Compara.
 GO:0060206; P:estrous cycle phase; IEP:RGD.
 GO:0042593; P:glucose homeostasis; IEA:Compara.
 GO:0003007; P:heart morphogenesis; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0007595; P:lactation; IEP:RGD.
 GO:0045599; P:negative regulation of fat cell differentiation; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0032355; P:response to estradiol stimulus; IEP:RGD.
 GO:0010243; P:response to organic nitrogen; IEP:RGD.
 GO:0021537; P:telencephalon development; IEA:Compara.
 GO:0050872; P:white fat cell differentiation; IEA:Compara. 
Interpro
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom. 
Pfam
 PF00249; Myb_DNA-binding 
SMART
 SM00717; SANT 
PROSITE
 PS51293; SANT 
PRINTS