UniProt Accession

 AHPC_BACSU; P80239; P53562 

Genbank Protein ID

 D78193; AL009126 

Genbank Nucleotide ID

 BAA11268.1; CAB16046.1 

Protein Name

 Alkyl hydroperoxide reductase subunit C 

Protein Synonyms/Alias

 Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase 

Gene Name

 ahpC 

Gene Synonyms/Alias

 BSU40090 

Created Date

 July 27, 2013 

Organism

 Bacillus subtilis (strain 168) 

NCBI Taxa ID

 224308 

Lysine Modification

Position	Peptide	Type	References
6	**MSLIGKEVLPFEA	acetylation	[1]
14	EVLPFEAKAFKNGEF	acetylation	[1]
88	GWHDSSEKISKITYA	acetylation	[1]

Reference

 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 

Functional Description

 Directly reduces organic hydroperoxides in its reduced dithiol form. 

Sequence Annotation

 DOMAIN 2 157 Thioredoxin.
 ACT_SITE 47 47 Cysteine sulfenic acid (-SOH)
 DISULFID 47 47 Interchain (with C-166); in linked form
 DISULFID 166 166 Interchain (with C-47); in linked form  

Keyword

 Antioxidant; Complete proteome; Direct protein sequencing; Disulfide bond; Oxidoreductase; Peroxidase; Redox-active center; Reference proteome; Stress response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 187 AA 

Protein Sequence

Gene Ontology

 GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
 GO:0051920; F:peroxiredoxin activity; IEA:EC.
 GO:0006979; P:response to oxidative stress; IEA:InterPro. 

Interpro

 IPR017559; AhpC.
 IPR000866; AhpC/TSA.
 IPR024706; Peroxiredoxin_AhpC-typ.
 IPR019479; Peroxiredoxin_C.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF10417; 1-cysPrx_C
 PF00578; AhpC-TSA 

SMART

  

PROSITE

 PS51352; THIOREDOXIN_2 

PRINTS