CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031211
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 7 
Protein Synonyms/Alias
 cDNA FLJ54719, highly similar to Zinc finger protein 7 
Gene Name
 ZNF7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
296FKCTECGKAFRLSSKubiquitination[1]
352YGCRECGKAFSQQSQubiquitination[2]
376GERPYPCKECGKAFSubiquitination[1]
404GEKAQILKASDSPSLubiquitination[1]
599YECSECGKAFSRSSYubiquitination[1]
680YKCNDCGKAFNRSSRubiquitination[1]
693SRLTQHQKIHMG***ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 697 AA 
Protein Sequence
MGFLGCWCVS FQEVVTFGDV AVHFSREEWQ CLDPGQRALY REVMLENHSS VAGLAGFLVF 60
KPELISRLEQ GEEPWVLDLQ GAEGTEAPRT SKTDSTIRTE NEQACEDMDI LKSESYGTVV 120
RISPQDFPQN PGFGDVSDSE VWLDSHLGSP GLKVTGFTFQ NNCLNEETVV PKTFTKDAPQ 180
GCKELGSSGL DCQPLESQGE SAEGMSQRCE ECGKGIRATS DIALHWEINT QKISRCQECQ 240
KKLSDCLQGK HTNNCHGEKP YECAECGKVF RLCSQLNQHQ RIHTGEKPFK CTECGKAFRL 300
SSKLIQHQRI HTGEKPYRCE ECGKAFGQSS SLIHHQRIHT GERPYGCREC GKAFSQQSQL 360
VRHQRTHTGE RPYPCKECGK AFSQSSTLAQ HQRMHTGEKA QILKASDSPS LVAHQRIHAV 420
EKPFKCDECG KAFRWISRLS QHQLIHTGEK PYKCNKCTKA FGCSSRLIRH QRTHTGEKPF 480
KCDECGKGFV QGSHLIQHQR IHTGEKPYVC NDCGKAFSQS SSLIYHQRIH KGEKPYECLQ 540
CGKAFSMSTQ LTIHQRVHTG ERPYKCNECG KAFSQNSTLF QHQIIHAGVK PYECSECGKA 600
FSRSSYLIEH QRIHTRAQWF YEYGNALEGS TFVSRKKVNT IKKLHQCEDC EKIFRWRSHL 660
IIHQRIHTGE KPYKCNDCGK AFNRSSRLTQ HQKIHMG 697 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS