CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044302
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nuclear pore complex protein Nup88 
Protein Synonyms/Alias
  
Gene Name
 NUP88 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
77LMVLELPKRWGKNSEubiquitination[1]
333SDFSCPVKLHRDPKCubiquitination[1, 2]
365TWIHKLHKFLGSDEEubiquitination[2]
374LGSDEEDKDSLQELSubiquitination[1, 3]
395VEHILCTKPLPCRQPubiquitination[1, 2]
470ETPDSFEKHIRSILQubiquitination[1, 3, 4]
585ADKYEEAKEKQEDIMubiquitination[2]
597DIMNRMKKLLHSFHSubiquitination[1]
618DSERDMKKELQLIPDubiquitination[1, 4]
635RHLGNAIKQVTMKKDubiquitination[1, 3]
647KKDYQQQKMEKVLSLubiquitination[1, 3]
650YQQQKMEKVLSLPKPubiquitination[1]
667ILSAYQRKCIQSILKubiquitination[1, 3]
674KCIQSILKEEGEHIRubiquitination[1, 3]
685EHIREMVKQINDIRNubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 696 AA 
Protein Sequence
XGLGGELFLW DGEDSSFLVV RLRGPSGGGE EPALSQYQRL LCINPPLFEI YQVLLSPTQH 60
HVALIGIKGL MVLELPKRWG KNSEFEGGKS TVNCSTTPVA ERFFTSSTSL TLKHAAWYPS 120
EILDPHVVLL TSDNVIRIYS LREPQTPTNV IILSEAEEES LVLNKGRAYT ASLGETAVAF 180
DFGPLAAVPK TLFGQNGKDE VVAYPLYILY ENGETFLTYI SLLHSPGNIG KLLGPLPMHP 240
AAEDNYGYDA CAVLCLPCVP NILVIATESG MLYHCVVLEG EEEDDHTSEK SWDSRIDLIP 300
SLYVFECVEL ELALKLASGE DDPFDSDFSC PVKLHRDPKC PSRYHCTHEA GVHSVGLTWI 360
HKLHKFLGSD EEDKDSLQEL STEQKCFVEH ILCTKPLPCR QPAPIRGFWI VPDILGPTMI 420
CITSTYECLI WPLLSTVHPA SPPLLCTRED VEVAESPLRV LAETPDSFEK HIRSILQRSV 480
ANPAFLNCFT QLRKIKVETL FLRASEKDIA PPPEECLQLL SRATQVFREQ YILKQDLAKE 540
EIQRRVKLLC DQKKKQLEDL SYCREERKSL REMAERLADK YEEAKEKQED IMNRMKKLLH 600
SFHSELPVLS DSERDMKKEL QLIPDQLRHL GNAIKQVTMK KDYQQQKMEK VLSLPKPTII 660
LSAYQRKCIQ SILKEEGEHI REMVKQINDI RNHVNF 696 
Gene Ontology
  
Interpro
 IPR019321; Nucleoporin_Nup88. 
Pfam
 PF10168; Nup88 
SMART
  
PROSITE
  
PRINTS