| Tag | Content |
|---|
| CPLM ID | CPLM-015228 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Caskin-1 |
Protein Synonyms/Alias | CASK-interacting protein 1 |
Gene Name | Caskin1 |
Gene Synonyms/Alias | Kiaa1306 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 522 | LTAIGVTKPGHRKKI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May link the scaffolding protein CASK to downstream intracellular effectors (By similarity). |
Sequence Annotation | REPEAT 48 77 ANK 1.
REPEAT 81 110 ANK 2.
REPEAT 114 143 ANK 3.
REPEAT 147 176 ANK 4.
REPEAT 188 217 ANK 5.
REPEAT 220 249 ANK 6.
DOMAIN 281 347 SH3.
DOMAIN 476 539 SAM 1.
DOMAIN 545 609 SAM 2.
REGION 375 471 CASK-binding (By similarity).
MOD_RES 253 253 Phosphotyrosine.
MOD_RES 650 650 Phosphoserine.
MOD_RES 779 779 Phosphothreonine.
MOD_RES 791 791 Phosphoserine.
MOD_RES 1067 1067 Phosphothreonine.
MOD_RES 1069 1069 Phosphoserine.
MOD_RES 1259 1259 Phosphoserine.
MOD_RES 1363 1363 Phosphoserine. |
Keyword | Alternative splicing; ANK repeat; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Repeat; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1431 AA |
Protein Sequence | MGKEQELVQA VKAEDVGTAQ RLLQRPRPGK AKLLGSTKKI NVNFQDPDGF SALHHAALNG 60
NTELISLLLE AQAAVDIKDN KGMRPLHYAA WQGRKEPMKL VLKAGSAVNV PSDEGHIPLH 120
LAAQHGHYDV SEMLLQHQSN PCMVDNSGKT PLDLACEFGR VGVVQLLLSS NMCAALLEPR 180
PGDTTDPNGT SPLHLAAKNG HIDIIRLLLQ AGIDINRQTK SGTALHEAAL CGKTEVVRLL 240
LDSGINAQVR NTYSQTALDI VHQFTTSQAS KEIKQLLREA SAALQVRATK DYCNNYDLTS 300
LNVKAGDIIT VLEQHPDGRW KGCIHDNRTG NDRVGYFPSS LGEAIVKRAG SRTGSEPSPP 360
QGGGSLGPSA PPEEIWVLRK PFAGGDRSGS LSNVAGGRST GGHALHAGSE GVKLLATVLS 420
QKSVSESSPG DSPVKPPEGS SGAARSQPPA AHAGQVYGEQ PPKKLESASA SASEGKSAEA 480
VSQWLATFQL QLYAPNFTSA GYDLPTISRM TPEDLTAIGV TKPGHRKKIT AEISGLNIPD 540
WLPEHKPANL AVWLSMIGLA QYYKVLVDNG YENIDFITDI TWEDLQEIGI TKLGHQKKLM 600
LAVRKLAELQ KAEYSKYEGG PLRRKTPQSL EMMAIESPPP SEPAAAECQS PKMTTFQDSE 660
LSGELQAALS GPAEAGAAAV EKSSNHLPPT PRTTSRESSL SGRARHISSS QELLGDGPPG 720
PGSPMSRSQE YLLDEGMAPG TPPKEVRSSR HGHSVKRASV PPVPGKPRQV LPSGASHFTP 780
PQTPTKAQPG SPQALGGPHG PATAKVKPTP QLLPPTDRPM SPRSLPQSPT HRGFAYVLPQ 840
PVEGEVGPPA PGPAPPPVPA AVPTLCLPPE TDVEPGRPKK RAHSLNRYAA SDSEPERDEL 900
LVPAAAGPYA TVQRRVGRSH SVRAPAGTDK NVNRSQSFAV RPRKKGPPPP PPKRSSSAMA 960
SANLADEPAP DVEAEDGRLG VRAQRRRASD LAGSVDTGSA GSVKSIAAML ELSSIGGGGR 1020
AIRRPPEGHP TPRPASPEPG RVATVLASVK HKEAIGPDGE VVNRRRTLSG PVTGLLATAR 1080
RGSGEPAEQS HFMEDGTARQ RLRGPAKGEA SAEGPPLARV EASATLKRRI RAKQSQQENV 1140
KFILTESDTV KRRPKAKEPD TGPEPPPPLS VYQNGTATVR RRPTSEQAGP PELPPPPPPA 1200
EPPPADLMQL PPLPLPDGNA RKPVKPPVSP KPILSQPVSK IQGSPTPASK KVPLPGPGSP 1260
EVKRAHGTPP PVSPKPPPPP TAPKPAKALA GLQSSSATPS PVPSPARQPP AALIKPASSP 1320
PSQSASPVKP PSPGTPALHV PAKPPRAAAS VVSGPPVASD CASPGDSARQ KLEETSACLA 1380
AALQAVEEKI RQEDGQGPRP SSIEEKSTGS ILEDIGSMFD DLADQLDAML E 1431 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |