| Tag | Content |
|---|
| CPLM ID | CPLM-006435 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2 |
Protein Synonyms/Alias | |
Gene Name | CSG2 |
Gene Synonyms/Alias | CLS2; YBR036C; YBR0404 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 127 | RIPAQQQKQKIISVA | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Required for calcium regulation. May regulate calcium accumulation by a non-vacuole organelle. Also regulates the activity of CSH1 and SUR1 during mannosyl phosphorylinositol ceramide synthesis. |
Sequence Annotation | CARBOHYD 35 35 N-linked (GlcNAc...) (Potential).
CARBOHYD 49 49 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 410 AA |
Protein Sequence | MSTTLLWFSS VIGYVIQTKC LSNIQSKKEI SVGPNGTIAT PETNGDNGNS SSLTFYLTFM 60
YFASWLLLVP ASRLWEKMRP MFVSDSDSNR NSQFDNNNSG SVTNEDVDTF SHVLDDPQPR 120
IPAQQQKQKI ISVATFKYVA KLTVLALIMI VADLTYNMAL SLSPAFDVAL MQNTAIFEIV 180
TLLYGVCGIS RKNYVFRNFL IMMNAVIGIL IISYTKATCD MLAGKLSVNP NTGELSDPFL 240
FDRLKGALIC GLGALIMGPF AVLWNRWFCS NISKNENSAV VLVKQSTHMA LIGIIGMVIL 300
LPFIPKFPSR ESVESISLFY NDKSFWFSLL GSIIFGSLPS LISILELNRK APAEYLTTCN 360
LGAIIFMGLA EWVCEPTQTT IVRWEVIGYI MLTVSLLVLS VTLGEGKYHH 410 |
Gene Ontology | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD. GO:0030234; F:enzyme regulator activity; IPI:SGD. GO:0006874; P:cellular calcium ion homeostasis; IMP:SGD. GO:0006688; P:glycosphingolipid biosynthetic process; ISS:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |