CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034700
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Kif21a 
Protein Synonyms/Alias
  
Gene Name
 Kif21a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
718KKLHAMNKELQRLQTacetylation[1]
1046KGLQAAQKEAQIKVLubiquitination[2]
1051AQKEAQIKVLEGRLKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1658 AA 
Protein Sequence
RIRPQLAKEK IEGCHICTSV TPGEPQVFLG KDKAFTFDYV FDIDSQQEQI YTQCIEKLIE 60
GCFEGYNATV FAYGQTGAGK TYTMGTGFDV NIMEEEQGII SRAVKHLFKS IEEKKTSAIK 120
NGVPPPEFKV NAQFLELYNE EVLDLFDTTR DIDAKNKKSN IRIHEDSTGG IYTVGVTTRT 180
VNTEPEMMQC LKLGALSRTT ASTQMNVQSS RSHAIFTIHV CQTRVCPQTD AENVTDNKMV 240
SESPQMNEFE TLTAKFHFVD LAGSERLKRT GATGERAKEG ISINCGLLAL GNVISALGDK 300
SKRATHVPYR DSKLTRLLQD SLGGNSQTIM IACVSPSDRD FMETLNTLKY ANRARNIKNK 360
VMVNQDRASQ QINALRSEIT RLQMELMEYK TGKRIIDEEG VESINDMFHE NAMLQTENNN 420
LRVRIKAMQE TVDALRARIT QLVSEQANQV LARAGEGNEE ISNMIHSYIK EIEDLRAKLL 480
ESEAVNENLR KSLTRATARS PFFSASSAFS STILSSDKET IEIIDLAKKD LEKLKRKEKR 540
KKKRLQKLEE SSREERSVAG KENNADPDQE KKEEKGVSEK ESSEVDVDEN QEASDHEDEE 600
DEEEEDEEED DIEGEESSDE SDSESDEKAN YQADLANITC EIAIKQKLID ELENSQKRLQ 660
TLKKQYEEKL MMLQHKIRDT QLERDQVLQN LGSVESYSEE KAKKVKCEYE KKLHAMNKEL 720
QRLQTAQKEH ARLLKNQSQY EKQLKKLQQD VTEMKKTKVR LMKQMKEEQE KARLTESRRN 780
REIAQLKKDQ RKRDHQLRLL EAQKRNQEVV LRRKTEEVTA LRRQVRPMSD KVAGKVTRKL 840
SSSESPTPDA GSSVTSGEAD ASRPGTQQKM RIPVARVQAL PTPTTNGTRK RYQRKGFTGR 900
VFTSKTARMK WQLLERRVTE IIMQKMTISN MEADMNRLLR QREELTKRRE KLSKRREKIA 960
KESGEGDKNL VNISEEMESL TANIDYINDS IADCQANIMQ MEEAKEEGET LDVTAVINAC 1020
TLTEARYLLD HFLSMGINKG LQAAQKEAQI KVLEGRLKQT EITSATQNQL LFHMLKEKAE 1080
LNPELDALLG NALQDLDSAP LEDEEDSSEE DGPLHSPGSE GSTLSSDLMK LCGEVKPKNK 1140
ARRRTTTQME LLYADSSEVA SDTSAGDASL PGPLTPVAEG QETGMNTETS VPSARDKELL 1200
PPSGLPPKIG SISRQPSVSE KKVPEPSPVT RRKAYEKADK AKTKEQKHSD SGASETSLSP 1260
PSSPPSRPRN ELNVFNRLTV SQGSAPVQQD KSDESDPSLS EVHRGIINPF PACRGIRASF 1320
LQCVHVAEGH TKAVLCVDST DDLLFTGSKD RTCKVWNLVT GQEIMSLGVH PNNVVSVKYC 1380
NYTSLVFTVS TSYIKVWDIR ESAKCIRTLT SSGQVTLGEA CSASTSRTVA IPSGESQINQ 1440
IALNPTGTFL YAASGNAVRM WDLKRFQSTG KLTGHLGPVM CLTVDQISNG QDLIITGSKD 1500
HYIKMFDVTE GALGTVSPTH NFEPPHYDGI EALAIQGDNL FSGSRDNGIK KWDLAQKGLL 1560
QQVPNAHKDW VCALGLVPGH PILLSGCRGG ILKLWNVDTF VPVGEMRGHD SPINAISVNS 1620
THVFTAADDR TVRIWKAHNL QDGQISDTGD PGEDSTSN 1658 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase.
 IPR009053; Prefoldin.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00225; Kinesin
 PF00400; WD40 
SMART
 SM00129; KISc
 SM00320; WD40 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00380; KINESINHEAVY.