CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005360
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 mRNA 3'-end-processing protein RNA14 
Protein Synonyms/Alias
  
Gene Name
 RNA14 
Gene Synonyms/Alias
 YMR061W; YM9796.14 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
407YEQELLYKQREKLTFubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. 
Sequence Annotation
 REPEAT 56 88 HAT 1.
 REPEAT 90 124 HAT 2.
 REPEAT 138 170 HAT 3.
 REPEAT 181 214 HAT 4.
 REPEAT 257 289 HAT 5.
 REPEAT 298 330 HAT 6.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 677 AA 
Protein Sequence
MSSSTTPDLL YPSADKVAEP SDNIHGDELR LRERIKDNPT NILSYFQLIQ YLETQESYAK 60
VREVYEQFHN TFPFYSPAWT LQLKGELARD EFETVEKILA QCLSGKLENN DLSLWSTYLD 120
YIRRKNNLIT GGQEARAVIV KAFQLVMQKC AIFEPKSSSF WNEYLNFLEQ WKPFNKWEEQ 180
QRIDMLREFY KKMLCVPFDN LEKMWNRYTQ WEQEINSLTA RKFIGELSAE YMKARSLYQE 240
WLNVTNGLKR ASPINLRTAN KKNIPQPGTS DSNIQQLQIW LNWIKWEREN KLMLSEDMLS 300
QRISYVYKQG IQYMIFSAEM WYDYSMYISE NSDRQNILYT ALLANPDSPS LTFKLSECYE 360
LDNDSESVSN CFDKCTQTLL SQYKKIASDV NSGEDNNTEY EQELLYKQRE KLTFVFCVYM 420
NTMKRISGLS AARTVFGKCR KLKRILTHDV YVENAYLEFQ NQNDYKTAFK VLELGLKYFQ 480
NDGVYINKYL DFLIFLNKDS QIKTLFETSV EKVQDLTQLK EIYKKMISYE SKFGNLNNVY 540
SLEKRFFERF PQENLIEVFT SRYQIQNSNL IKKLELTYMY NEEEDSYFSS GNGDGHHGSY 600
NMSSSDRKRL MEETGNNGNF SNKKFKRDSE LPTEVLDLLS VIPKRQYFNT NLLDAQKLVN 660
FLNDQVEIPT VESTKSG 677 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005849; C:mRNA cleavage factor complex; IPI:SGD.
 GO:0006379; P:mRNA cleavage; IDA:SGD.
 GO:0006378; P:mRNA polyadenylation; IDA:SGD. 
Interpro
 IPR003107; HAT.
 IPR008847; Suf.
 IPR011990; TPR-like_helical. 
Pfam
 PF05843; Suf 
SMART
 SM00386; HAT 
PROSITE
  
PRINTS