UniProt Accession

 RS21A_YEAST; P0C0V8; D6VXB8; P05760 

Genbank Protein ID

 X07811; Z28282; Z28283; BK006944 

Genbank Nucleotide ID

 CAA30671.1; CAA82135.1; CAA82137.1; DAA09208.1 

Protein Name

 40S ribosomal protein S21-A 

Protein Synonyms/Alias

 S26; YS25 

Gene Name

 RPS21A 

Gene Synonyms/Alias

 RPS25; RPS25A; RPS26A; YKR057W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
5	***MENDKGQLVELY	acetylation	[1]
38	SVQINVAKVDEEGRA	acetylation	[1]
38	SVQINVAKVDEEGRA	ubiquitination	[2]
80	AQNDGLLKNVWSYSR	acetylation	[1]
80	AQNDGLLKNVWSYSR	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. 

Sequence Annotation

 MOD_RES 1 1 N-acetylmethionine.  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Ribonucleoprotein; Ribosomal protein; rRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 87 AA 

Protein Sequence

Gene Ontology

 GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IC:SGD.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0006414; P:translational elongation; IBA:RefGenome. 

Interpro

 IPR001931; Ribosomal_S21e.
 IPR018279; Ribosomal_S21e_CS. 

Pfam

 PF01249; Ribosomal_S21e 

SMART

  

PROSITE

 PS00996; RIBOSOMAL_S21E 

PRINTS