CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045126
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Hepatoma-derived growth factor-related protein 2 
Protein Synonyms/Alias
  
Gene Name
 HDGFRP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39AVKPPPNKYPIFFFGacetylation[1, 2, 3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 675 AA 
Protein Sequence
MPHAFKPGDL VFAKMKGYPH WPARIDDIAD GAVKPPPNKY PIFFFGTHET AFLGPKDLFP 60
YDKCKDKYGK PNKRKGFNEG LWEIQNNPHA SYSAPPPVSS SDSEAPEANP ADGSDADEDD 120
EDRGVMAVTA VTATAASDRM ESDSDSDKSS DNSGLKRKTP ALKMSVSKRA RKASSDLDQA 180
SVSPSEEENS ESSSESEKTS DQDFTPEKKA AVRAPRRGPL GGRKKKKAPS ASDSDSKADS 240
DGAKPEPVAM ARSASSSSSS SSSSDSDVSV KKPPRGRKPA EKPLPKPRGR KPKPERPPSS 300
SSSDSDSDEV DRISEWKRRD EARRRELEAR RRREQEEELR RLREQEKEEK ERRRERADRG 360
EAERGSGGSS GDELREDDEP VKKRGRKGRG RGPPSSSDSE PEAELEREAK KSAKKPQSSS 420
TEPARKPGQK EKRVRPEEKQ QAKPVKVERT RKRSEGFSMD RKVEKKKEPS VEEKLQKLHS 480
EIKFALKVDS PDVKRCLNAL EELGTLQVTS QILQKNTDVV ATLKKIRRYK ANKDVMEKAA 540
EVYTRLKSRV LGPKIEAVQK VNKAGMEKEK AEEKLAGEEL AGEELAGEEA PQEKAEDKPS 600
TDLSAPVNGE ATSQKGESAE DKEHEEGRDS EEGPRCGSSE DLHDVREGPD LDRPGSDRQE 660
RERARGDSEA LDEES 675 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR021567; LEDGF.
 IPR000313; PWWP.
 IPR017923; TFIIS_N. 
Pfam
 PF11467; LEDGF
 PF00855; PWWP 
SMART
 SM00293; PWWP 
PROSITE
 PS50812; PWWP 
PRINTS