CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041851
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Muscleblind-like 1 (Drosophila), isoform CRA_a 
Protein Synonyms/Alias
 Muscleblind-like protein 1 
Gene Name
 Mbnl1 
Gene Synonyms/Alias
 mCG_19416 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
58IACFDSLKGRCSRENacetylation[1]
58IACFDSLKGRCSRENubiquitination[2]
245PPAHLQAKIKAAQYQubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 381 AA 
Protein Sequence
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR 60
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV 120
APSLATSASA AFNPYLGPVS PSLVPAEILP TAPMLVTGNP GVPVPAAAAA AAQKLMRTDR 180
LEVCREYQRG NCNRGENDCR FAHPADSTMI DTNDNTVTVC MDYIKGRCSR EKCKYFHPPA 240
HLQAKIKAAQ YQVNQAAAAQ AAATAAAMGI PQAVLPPLPK RPALEKTNGA TAVFNTGIFQ 300
YQQALANMQL QQHTAFLPPG SILCMTPATS VVPMVHGATP ATVSAATTSA TSVPFAATAT 360
ANQIPIISAE HLTSHKYVTQ M 381 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0010494; C:cytoplasmic stress granule; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003725; F:double-stranded RNA binding; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0000380; P:alternative mRNA splicing, via spliceosome; IMP:MGI.
 GO:0006376; P:mRNA splice site selection; IMP:MGI.
 GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:MGI.
 GO:0007519; P:skeletal muscle tissue development; IMP:MGI. 
Interpro
 IPR000571; Znf_CCCH. 
Pfam
  
SMART
 SM00356; ZnF_C3H1 
PROSITE
 PS50103; ZF_C3H1 
PRINTS