CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042905
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
433PVSLESKKAARAARFubiquitination[1]
512TTEDTEAKKRKRAERubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Chaperone; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 523 AA 
Protein Sequence
XPALQRCLTL LRDSRPWQRL VRIVQWGWLE LPWVKQNINR QGNAPVASGR YCQPEEEVAR 60
LLTMAGVPED ELNPFHVLGV EATASDVELK KAYRQLAVMV HPDKNHHPRA EEAFKVLRAA 120
WDIVSNAEKR KEYEMKRMAE NELSRSVNEF LSKLQDDLKE AMNTMMCSRC QGKHRRFEMD 180
REPKSARYCA ECNRLHPAEE GDFWAESSML GLKITYFALM DGKVYDITEW AGCQRVGISP 240
DTHRVPYHIS FGSRIPGTRG RQRATPDAPP ADLQDFLSRI FQVPPGQMPN GNFFAAPQPA 300
PGAAAASKPN STVPKGEAKP KRRKKLAELK QECLARGLET KGIKQDLIHR LQAYLEEHAE 360
EEANEEDVLG DETEEEETKP IELPVKEEEP PEKTVDVAAE KKVVKITSEI PQTERMQKRA 420
ERFNVPVSLE SKKAARAARF GISSVPTKGL SSDNKPMVNL DKLKERAQRF GLNVSSISRK 480
SEDDEKLKKR KERFGIVTSS AGTGTTEDTE AKKRKRAERF GIA 523 
Gene Ontology
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR001623; DnaJ_domain.
 IPR003034; SAP_dom. 
Pfam
 PF00226; DnaJ
 PF02037; SAP 
SMART
 SM00271; DnaJ
 SM00513; SAP 
PROSITE
 PS50076; DNAJ_2
 PS50800; SAP 
PRINTS
 PR00625; JDOMAIN.