CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027105
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Rela 
Protein Synonyms/Alias
 RELA; V-rel reticuloendotheliosis viral oncogene homolog A (Avian) 
Gene Name
 Rela 
Gene Synonyms/Alias
 RelA; rCG_48632 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
310KRTYETFKSIMKKSPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 550 AA 
Protein Sequence
MDDLFPLIFP SEPAQASGPY VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT 60
IKINGYTGPG TVRISLVTKD PPHRPHPHEL VGKDCRDGFY EAELCPDRCI HSFQNLGIQC 120
VKKRDLEQAI SQRIQTNNNP FQVPIEEQRG DYDLNAVRLC FQVTVRDPSG RPLRLTPVLS 180
HPIFDNRAPN TAELKICRVN RNSGSCLGGD EIFLLCDKVQ KEDIEVYFTG PGWEARGSFS 240
QADVHRQVAI VFRTPPYADP SLQAPVRVSM QLRRPSDREL SEPMEFQYLP DTDDRHRIEE 300
KRKRTYETFK SIMKKSPFNG PTEPRPPPRR IAVPSRGPTS VPKPAPQPYA FSTSLSTINF 360
DEFSPMVLPP GQISNQALAL APSSAPVLAQ TMVPSSAMVP SLAQPPAPVP VLAPGPPQSL 420
SAPVPKSTQA GEGTLSEALL HLQFDADEDL GALLGNNTDP GVFTDLASVD NSEFQQLLNQ 480
GVAMSHSTAE PMLMEYPEAI TRLVTGSQRP PDPAPATLGT SGLPNGLSGD EDFSSIADMD 540
FSALLSQISS 550 
Gene Ontology
 GO:0005829; C:cytosol; IDA:RGD.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0042301; F:phosphate ion binding; IEA:Compara.
 GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IDA:RGD.
 GO:0044212; F:transcription regulatory region DNA binding; IEA:Compara.
 GO:0006117; P:acetaldehyde metabolic process; IEP:RGD.
 GO:0007568; P:aging; IEP:RGD.
 GO:0071347; P:cellular response to interleukin-1; IEA:Compara.
 GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.
 GO:0071356; P:cellular response to tumor necrosis factor; IEA:Compara.
 GO:0019221; P:cytokine-mediated signaling pathway; IEA:Compara.
 GO:0001942; P:hair follicle development; IEA:Compara.
 GO:0006954; P:inflammatory response; IEA:Compara.
 GO:0001889; P:liver development; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.
 GO:0042177; P:negative regulation of protein catabolic process; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IEA:Compara.
 GO:0009887; P:organ morphogenesis; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.
 GO:0032332; P:positive regulation of chondrocyte differentiation; IMP:RGD.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara.
 GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Compara.
 GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0014040; P:positive regulation of Schwann cell differentiation; IMP:RGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0050727; P:regulation of inflammatory response; IEA:Compara.
 GO:0043200; P:response to amino acid stimulus; IEP:RGD.
 GO:0051591; P:response to cAMP; IEP:RGD.
 GO:0033590; P:response to cobalamin; IEP:RGD.
 GO:0034097; P:response to cytokine stimulus; IEP:RGD.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0042542; P:response to hydrogen peroxide; IEP:RGD.
 GO:0032868; P:response to insulin stimulus; IEP:RGD.
 GO:0009612; P:response to mechanical stimulus; IEP:RGD.
 GO:0043278; P:response to morphine; IEP:RGD.
 GO:0032495; P:response to muramyl dipeptide; IEA:Compara.
 GO:0032570; P:response to progesterone stimulus; IEP:RGD.
 GO:0010224; P:response to UV-B; IEA:Compara. 
Interpro
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002909; IPT_TIG_rcpt.
 IPR000451; NF_Rel_Dor.
 IPR008967; p53-like_TF_DNA-bd.
 IPR011539; RHD. 
Pfam
 PF00554; RHD 
SMART
 SM00429; IPT 
PROSITE
 PS01204; REL_1
 PS50254; REL_2 
PRINTS
 PR00057; NFKBTNSCPFCT.