CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025077
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Nle1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
323QDLQGSLKELKERASubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Nucleus; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 485 AA 
Protein Sequence
MAAAVVEEAA AGDVQRLLVQ FQDEGGQLLG SPFDVPVDIT PDKLQLVCNA LLAQEEPLPL 60
AFYVHDAEIV SSLGKTLESQ SVETEKIVDN IYQPQAVFRV RAVTRCTSSL EGHSEAVISV 120
AFSPTGKYLA SGSGDTTVRF WDLSTETPHF TCKGHRHWVL SISWSPDGKK LASGCKNGQV 180
LLWDPSTGLQ VGRTLTDHSI WITGLSWEPL HMNPECRYVA SSSKDGSVRV WDTTAGRCER 240
ILTGHTQSVT CLRWGGDGLL YSASQDRTIK VWRAHDGVLC RTLQGHGHWV NTMALSTDYA 300
LRTGAFEPAE ATVNAQDLQG SLKELKERAS SRYNLVRGQG PERLVSGSDD FTLFLWSPAE 360
DKKPLARMTG HQALINQVLF SPDSRIVASA SFDKSIKLWD GRTGKYLASL RGHVAAVYQI 420
AWSADSRLLV SGSSDSTLKV WDVKAQKLAT DLPGHADEVY AVDWSPDGQR VASGGKDKCL 480
RIWRR 485 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0001826; P:inner cell mass cell differentiation; IMP:MGI.
 GO:0007219; P:Notch signaling pathway; IDA:MGI. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR001632; Gprotein_B.
 IPR012972; NLE.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF08154; NLE
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00319; GPROTEINB.
 PR00320; GPROTEINBRPT.