CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007040
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 26S proteasome regulatory subunit RPN10 
Protein Synonyms/Alias
  
Gene Name
 RPN10 
Gene Synonyms/Alias
 MCB1; SUN1; YHR200W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
71TFTAEFGKILAGLHDubiquitination[1, 2]
84HDTQIEGKLHMATALubiquitination[2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Multiubiquitin binding protein. 
Sequence Annotation
 DOMAIN 5 190 VWFA.
 REPEAT 223 242 UIM.  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 268 AA 
Protein Sequence
MVLEATVLVI DNSEYSRNGD FPRTRFEAQI DSVEFIFQAK RNSNPENTVG LISGAGANPR 60
VLSTFTAEFG KILAGLHDTQ IEGKLHMATA LQIAQLTLKH RQNKVQHQRI VAFVCSPISD 120
SRDELIRLAK TLKKNNVAVD IINFGEIEQN TELLDEFIAA VNNPQEETSH LLTVTPGPRL 180
LYENIASSPI ILEEGSSGMG AFGGSGGDSD ANGTFMDFGV DPSMDPELAM ALRLSMEEEQ 240
QRQERLRQQQ QQQDQPEQSE QPEQHQDK 268 
Gene Ontology
 GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
 GO:0031593; F:polyubiquitin binding; IDA:SGD.
 GO:0005198; F:structural molecule activity; IMP:SGD.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD. 
Interpro
 IPR027040; Proteasome_su_Rpn10.
 IPR003903; Ubiquitin-int_motif.
 IPR002035; VWF_A. 
Pfam
  
SMART
 SM00726; UIM
 SM00327; VWA 
PROSITE
 PS50330; UIM
 PS50234; VWFA 
PRINTS