CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000507
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Methylthioribose-1-phosphate isomerase 
Protein Synonyms/Alias
 M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase 
Gene Name
 mtnA 
Gene Synonyms/Alias
 ykrS; BSU13550 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
38EYLELTTKEDVFDAIacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). 
Sequence Annotation
 REGION 51 53 Substrate binding.
 REGION 250 251 Substrate binding.
 ACT_SITE 240 240 Proton donor.
 BINDING 94 94 Substrate.
 BINDING 199 199 Substrate.  
Keyword
 3D-structure; Amino-acid biosynthesis; Complete proteome; Isomerase; Methionine biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 353 AA 
Protein Sequence
MTHSFAVPRS VEWKETAITI LNQQKLPDET EYLELTTKED VFDAIVTLKV RGAPAIGITA 60
AFGLALAAKD IETDNVTEFR RRLEDIKQYL NSSRPTAINL SWALERLSHS VENAISVNEA 120
KTNLVHEAIQ IQVEDEETCR LIGQNALQLF KKGDRIMTIC NAGSIATSRY GTALAPFYLA 180
KQKDLGLHIY ACETRPVLQG SRLTAWELMQ GGIDVTLITD SMAAHTMKEK QISAVIVGAD 240
RIAKNGDTAN KIGTYGLAIL ANAFDIPFFV AAPLSTFDTK VKCGADIPIE ERDPEEVRQI 300
SGVRTAPSNV PVFNPAFDIT PHDLISGIIT EKGIMTGNYE EEIEQLFKGE KVH 353 
Gene Ontology
 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IBA:RefGenome.
 GO:0019284; P:L-methionine biosynthetic process from S-adenosylmethionine; IEA:HAMAP.
 GO:0019509; P:L-methionine salvage from methylthioadenosine; IBA:RefGenome. 
Interpro
 IPR000649; IF-2B-related.
 IPR005251; IF-2BI_MTNA.
 IPR011559; Initiation_fac_2B_a/b/d.
 IPR027363; M1Pi_N. 
Pfam
 PF01008; IF-2B 
SMART
  
PROSITE
  
PRINTS