| Tag | Content |
|---|
| CPLM ID | CPLM-019762 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cell growth regulator with RING finger domain protein 1 |
Protein Synonyms/Alias | Cell growth regulatory gene 19 protein; RING finger protein 197 |
Gene Name | CGRRF1 |
Gene Synonyms/Alias | CGR19; RNF197 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 159 | CQLPRDTKIEDFGTV | ubiquitination | [1] | | 247 | NNSSSEEKNTDRSLL | ubiquitination | [1] | | 256 | TDRSLLEKVGLSESE | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Able to inhibit growth in several cell lines (By similarity). |
Sequence Annotation | ZN_FING 274 309 RING-type. |
Keyword | 3D-structure; Cell cycle; Complete proteome; Growth arrest; Metal-binding; Nucleus; Polymorphism; Reference proteome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 332 AA |
Protein Sequence | MAAVFLVTLY EYSPLFYIAV VFTCFIVTTG LVLGWFGWDV PVILRNSEET QFSTRVFKKQ 60
MRQVKNPFGL EITNPSSASI TTGITLTTDC LEDSLLTCYW GCSVQKLYEA LQKHVYCFRI 120
STPQALEDAL YSEYLYQEQY FIKKDSKEEI YCQLPRDTKI EDFGTVPRSR YPLVALLTLA 180
DEDDREIYDI ISMVSVIHIP DRTYKLSCRI LYQYLLLAQG QFHDLKQLFM SANNNFTPSN 240
NSSSEEKNTD RSLLEKVGLS ESEVEPSEEN SKDCVVCQNG TVNWVLLPCR HTCLCDGCVK 300
YFQQCPMCRQ FVQESFALCS QKEQDKDKPK TL 332 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW. GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. GO:0006950; P:response to stress; TAS:ProtInc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |