CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005035
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myb-like DNA-binding protein BAS1 
Protein Synonyms/Alias
  
Gene Name
 BAS1 
Gene Synonyms/Alias
 YKR099W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
690SSSVTTNKFNHIDQSacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Activates HIS4 transcription only in combination with PHO2/BAS2. BAS1 is also involved in the regulation of the purine biosynthesis pathway. 
Sequence Annotation
 DOMAIN 34 110 Myb-like.
 DOMAIN 111 165 HTH myb-type 1.
 DOMAIN 166 218 HTH myb-type 2.
 DNA_BIND 138 161 H-T-H motif (By similarity).
 DNA_BIND 191 214 H-T-H motif (By similarity).  
Keyword
 Activator; Complete proteome; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 811 AA 
Protein Sequence
MSNISTKDIR KSKPKRGSGF DLLEVTESLG YQTHRKNGRN SWSKDDDNML RSLVNESAKE 60
LGYENGLEDV KTIQQSNHLS KCIAWDVLAT RFKHTVRTSK DVRKRWTGSL DPNLKKGKWT 120
QEEDEQLLKA YEEHGPHWLS ISMDIPGRTE DQCAKRYIEV LGPGSKGRLR EWTLEEDLNL 180
ISKVKAYGTK WRKISSEMEF RPSLTCRNRW RKIITMVVRG QASEVITKAI KENKNIDMTD 240
GKLRQHPIAD SDIRSDSTPN KEEQLQLSQQ NNPSLIKQDI LNVKENESSK LPRLKDNDGP 300
ILNDSKPQAL PPLKEISAPP PIRMTQVGQT HTSGSIRSKV SLPIEGLSQM NKQSPGGISD 360
SPQTSLPPAF NPASLDEHMM NSNSISDSPK HAYSTVKTRE PNSSSTQWKF TLKDGQGLSI 420
SNGTIDSTKL VKELVDQAKK YSLKISIHQH IHNHYVTSTD HPVSSNTGLS NIGNINGNPL 480
LMDSFPHMGR QLGNGLPGLN SNSDTFNPEY RTSLDNMDSD FLSRTPNYNA FSLEATSHNP 540
ADNANELGSQ SNRETNSPSV FYPQANTLIP TNSTATNNEI IQGNVSANSM SPNFNGTNGK 600
APSSTASYTT SGSEMPPDVG PNRIAHFNYL PPTIRPHLGS SDATRGADLN KLLNPSPNSV 660
RSNGSKTKKK EKRKSESSQH HSSSSVTTNK FNHIDQSEIS RTTSRSDTPL RDEDGLDFWE 720
TLRSLATTNP NPPVEKSAEN DGAKPQVVHQ GIGSHTEDSS LGSHSGGYDF FNELLDKKAD 780
TLHNEAKKTS EHDMTSGGST DNGSVLPLNP S 811 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0001046; F:core promoter sequence-specific DNA binding; IDA:SGD.
 GO:0001135; F:RNA polymerase II transcription factor recruiting transcription factor activity; IMP:SGD.
 GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IMP:SGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD. 
Interpro
 IPR009057; Homeodomain-like.
 IPR017877; Myb-like_dom.
 IPR017930; Myb_dom.
 IPR001005; SANT/Myb. 
Pfam
 PF00249; Myb_DNA-binding 
SMART
 SM00717; SANT 
PROSITE
 PS51294; HTH_MYB
 PS50090; MYB_LIKE 
PRINTS