CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027133
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glyceraldehyde-3-phosphate dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Xenopus laevis (African clawed frog) 
NCBI Taxa ID
 8355 
Lysine Modification
Position
Peptide
Type
References
192TVDGPSGKLWRDGRGacetylation[1]
249DLTCRLQKPAKYDDIacetylation[1]
252CRLQKPAKYDDIKAAacetylation[1]
Reference
 [1] A biotin switch-based proteomics approach identifies 14-3-3ΞΆ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 333 AA 
Protein Sequence
MVKVGINGFG RIGRLVTRAA FDSGKVQVTA INDPFIDLDY MVYMFKYDST HGRFKGTVKA 60
ENGKLIINDQ VITVFQERDP SNIKWGDAGA VYVVESTGVF TTTEKASLHL KGGAKRVVIS 120
APSADAPMFV VGVNHEKYEN SLKVVSNASC TTNCLAPLAK VINDNFGIVE GLMTTVHAFT 180
ATQKTVDGPS GKLWRDGRGA GQNIIPASTG AAKAVGKVIP ELNGKITGMA FRVPTPNVSV 240
VDLTCRLQKP AKYDDIKAAI KTASEGPMKG ILGYTQDQVV STDFNGDTHS SIFDADAGIA 300
LNENFVKLVS WYDNECGYSH RVVDLMCHMA SKE 333 
Gene Ontology
 GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; IEA:EC.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006006; P:glucose metabolic process; IEA:InterPro. 
Interpro
 IPR020831; GlycerAld/Erythrose_P_DH.
 IPR020830; GlycerAld_3-P_DH_AS.
 IPR020829; GlycerAld_3-P_DH_cat.
 IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
 IPR006424; Glyceraldehyde-3-P_DH_1.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02800; Gp_dh_C
 PF00044; Gp_dh_N 
SMART
 SM00846; Gp_dh_N 
PROSITE
 PS00071; GAPDH 
PRINTS
 PR00078; G3PDHDRGNASE.