| Tag | Content |
|---|
| CPLM ID | CPLM-018622 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | FERM domain-containing protein 4B |
Protein Synonyms/Alias | GRP1-binding protein GRSP1; Golgi-associated band 4.1-like protein; GOBLIN |
Gene Name | Frmd4b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 78 | LELLVQPKLLSRELL | ubiquitination | [1] | | 95 | VASHFNLKEKEYFGI | ubiquitination | [1] | | 440 | KEKLLQEKLLQKVEE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein. |
Sequence Annotation | DOMAIN 59 361 FERM.
MOD_RES 609 609 Phosphoserine (By similarity).
MOD_RES 675 675 Phosphotyrosine.
MOD_RES 698 698 Phosphoserine.
MOD_RES 916 916 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1035 AA |
Protein Sequence | MASVFMCGVE DLLFSGSRFV WNLTVSTLRR WYTERLRACH QVLRTWCGLR DVYQMTEGRH 60
CQVHLLDDRR LELLVQPKLL SRELLDLVAS HFNLKEKEYF GITFIDDTGQ ENWLQLDHRV 120
LEHDLPKKPG PTLLHFAVRF YIESISFLKD KNTVELFFLN AKACVHKGQI EVDSETIFKL 180
AALVLQESKG DYTSDENARK DLKTLPVFPT KTLQEHPSLA YCEDRVIEHY LKIKGLTRGQ 240
AVVQYMKIVE ALPTYGVHYY AVKDKQGLPW WLGISYKGIG QYDLQDKVKP RKLFQWKQLE 300
NLYFREKKFA VEVHDPRRIS VSRRTFGQSG LFVQTWYANS SLIKSIWVMA ISQHQFYLDR 360
KQSKAKIPSA RSLDDIAMDL TETGTQRGSK LVTLEAKSQF IMASNGSLIS SGSQDSEGME 420
EQKREKILEL KKKEKLLQEK LLQKVEELKK ICLREAELTG RMPKEYPLNI GEKPPQVRRR 480
VGTTFKLDDN LLPTEEDPAL QELESNFLIQ QKLVEAAKKL ASEPDLCKTV KKKRKQDYTD 540
AVKRLQEIEN SINEYRIRCG KKPSQKAAVV PPEDIIPSES SSLSDTTTYD DPNDSFTLAG 600
QRPSSVPHSP RILPPKSLGI ERIHFRKSSI NEQFMDTRHS REMLSTHSSP YKTLERRPQG 660
GRSMPTTPVL TRNAYSSSHL EPDSSSQHCR QRSGSLESQS HLLSEMDSDK PFFTLSKSQR 720
SSSTEILDDG SSYTSQSSSE YYCVTPAASP YYTTQTLDTR ARGRRRSKKH SVSTSNSGSM 780
PNLAQKDPLR NGVYSKGQDP PPSGYYIAGY PPYAECDLYY SGGYVYENDT EGQYSVNPSY 840
RSSAHYGYDR QRDYSRSFHE DEVDRVPHNP YATLRLPRKA AVKSEHITKN IHKALVAEHL 900
RGWYQRASGQ KDQGHSPQTS FDSDRGSQRC LGFAGLQVPC SPSSRASSYS SVSSTNASGN 960
WRTQLTIGLS EYENPVHSPY TSYYGSIYNP LSSPSRQYAE TTPLDGTDGS QLEDNLEGSE 1020
QRLFWHEDSK PGTLV 1035 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |