| Tag | Content |
|---|
| CPLM ID | CPLM-013019 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Trimeric intracellular cation channel type A |
Protein Synonyms/Alias | TRIC-A; TRICA; 27 kDa sarcoplasmic reticulum protein; Mitsugumin-33A; SPR-27; Transmembrane protein 38A |
Gene Name | Tmem38a |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 282 | SGLPAKAKEELGEGS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. |
Sequence Annotation | |
Keyword | Complete proteome; Ion channel; Ion transport; Membrane; Nucleus; Potassium; Potassium channel; Potassium transport; Reference proteome; Sarcoplasmic reticulum; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 298 AA |
Protein Sequence | MDLMSALSLG ELALSFSRVP LFPVFDLSYF IVSIIYLKYE PGAVELSRRH PVASWLCAML 60
HCFGSYILAD LLLGEPIIDY FSNSSSILLA SGVWYLIFFC PLDLFYKCVC FLPVKLIFVA 120
MKEVVRVRKI AVGIHHAHHH YHHGWFIMIA TGWVKGSGVA LLSNVEQLLR GVWKPETNEI 180
LHMSFPTKAS LYGAILFTLQ QTRWLPVSKA SLIFVFTMFM VSCKVFLTAT HSHSSPFDIL 240
EGYICPVLFG ATWGGDHHHD NHGAPHGMGL GTQHSGLPAK AKEELGEGSR KKKTKKAD 298 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0015269; F:calcium-activated potassium channel activity; TAS:BHF-UCL. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |