UniProt Accession

 SNU13_YEAST; P39990; D3DLM2 

Genbank Protein ID

 U18530; AY558377; BK006939 

Genbank Nucleotide ID

 AAB64503.1; AAS56703.1; DAA07626.1 

Protein Name

 13 kDa ribonucleoprotein-associated protein 

Protein Synonyms/Alias

 Small nuclear ribonucleoprotein-associated protein 1 

Gene Name

 SNU13 

Gene Synonyms/Alias

 YEL026W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
118	KTQIYAVKDKIETLL	ubiquitination	[1]
120	QIYAVKDKIETLLI*	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; RNA-binding; rRNA processing; Spliceosome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 126 AA 

Protein Sequence

Gene Ontology

 GO:0031428; C:box C/D snoRNP complex; IDA:SGD.
 GO:0032040; C:small-subunit processome; IDA:SGD.
 GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
 GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000398; P:mRNA splicing, via spliceosome; IMP:SGD. 

Interpro

 IPR002415; H/ACA_rnp_Nhp2_euk.
 IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
 IPR018492; Ribosomal_L7Ae/L8/Nhp2.
 IPR004037; Ribosomal_L7Ae_CS. 

Pfam

 PF01248; Ribosomal_L7Ae 

SMART

  

PROSITE

 PS01082; RIBOSOMAL_L7AE 

PRINTS

 PR00881; L7ARS6FAMILY.
 PR00883; NUCLEARHMG.