CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029185
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 
Protein Synonyms/Alias
  
Gene Name
 PIP5K1A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
194KEAEFLQKLLPGYYMubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 550 AA 
Protein Sequence
MASASSGPSS SVGFSSFDPA VPSCTLSSAA SGIKRPMASE VPYASGMPIK KIGHRSVDSS 60
GETTYKKTTS SALKGAIQLG ITHTVGSLST KPERDVLMQD FYVVESIFFP SEGSNLTPAH 120
HYNDFRFKTY APVAFRYFRE LFGIRPDDYL YSLCSEPLIE LCSSGASGSL FYVSSDDEFI 180
IKTVQHKEAE FLQKLLPGYY MNLNQNPRTL LPKFYGLYCV QAGGKNIRIV VMNNLLPRSV 240
KMHIKYDLKG STYKRRASQK EREKPLPTFK DLDFLQDIPD GLFLDADMYN ALCKTLQRDC 300
LVLQSFKIMD YSLLMSIHNI DHAQREPLSS ETQYSVDTRR PAPQKALYST AMESIQGEAR 360
RGGTMETDDH MGGIPARNSK GERLLLYIGI IDILQSYRFV KKLEHSWKAL VHDGDTVSVH 420
RPGFYAERFQ RFMCNTVFKK IPLKPSPSKK FRSGSSFSRR AGSSGNSCIT YQPSVSGEHK 480
AQVTTKAEVE PGVHLGRPDV LPQTPPLEEI SEGSPIPDPS FSPLVGETLQ MLTTSTTLEK 540
LEVAESEFTH 550 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0016307; F:phosphatidylinositol phosphate kinase activity; IEA:InterPro.
 GO:0046854; P:phosphatidylinositol phosphorylation; IEA:GOC. 
Interpro
 IPR023610; PInositol-4-P-5-kinase.
 IPR027483; PInositol-4-P-5-kinase_C.
 IPR002498; PInositol-4-P-5-kinase_core.
 IPR027484; PInositol-4-P-5-kinase_N.
 IPR016034; PInositol-4P-5-kinase_core_sub. 
Pfam
 PF01504; PIP5K 
SMART
 SM00330; PIPKc 
PROSITE
 PS51455; PIPK 
PRINTS