UniProt Accession

 B4DED4_HUMAN; B4DED4 

Genbank Protein ID

 Z98258; AK293575; CH471112 

Genbank Nucleotide ID

 BAG57045.1; EAW85728.1 

Protein Name

 Hydroxyacylglutathione hydrolase-like protein 

Protein Synonyms/Alias

 Hydroxyacylglutathione hydrolase-like, isoform CRA_d; cDNA FLJ58840, highly similar to Homo sapiens hydroxyacylglutathione hydrolase-like (HAGHL), transcript variant 2, mRNA 

Gene Name

 HAGHL 

Gene Synonyms/Alias

 hCG_22423 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
34	AVDVAVPKRLLEIVG	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 227 AA 

Protein Sequence

Gene Ontology

 GO:0004416; F:hydroxyacylglutathione hydrolase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006750; P:glutathione biosynthetic process; IEA:InterPro. 

Interpro

 IPR001279; Beta-lactamas-like.
 IPR017782; Hydroxyacylglutathione_Hdrlase. 

Pfam

 PF00753; Lactamase_B 

SMART

 SM00849; Lactamase_B 

PROSITE

  

PRINTS