CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034177
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Propionyl-CoA carboxylase beta chain, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Pccb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
62RRIDAQHKRFPGDSVacetylation[1]
210QEQLGGAKTHTTVSGacetylation[2]
210QEQLGGAKTHTTVSGsuccinylation[2]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 256 AA 
Protein Sequence
MAAAIRIRAV AAGARLSVLN CGLGITTRGL CSQPVSVKER IDNKRHAALL GGGQRRIDAQ 60
HKRFPGDSVV TGRGRINGRL VYVFSQDFTV FGGSLSGAHA QKICKIMDQA ITVGAPVIGL 120
NDSGGARIQE GVESLAGYAD IFLRNVTASG VIPQISLIMG PCAGGAVYSP ALTDFTFMVK 180
DTSYLFITGP EVVKSVTNED VTQEQLGGAK THTTVSGVAH RAFDNDVDAL CNLREFFNFL 240
PLSSQDPAPI RECHDP 256 
Gene Ontology
 GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
 GO:0004658; F:propionyl-CoA carboxylase activity; ISS:MGI.
 GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro. 
Interpro
 IPR000438; Acetyl_CoA_COase_Trfase_b_su.
 IPR000022; Carboxyl_trans.
 IPR011763; COA_CT_C.
 IPR011762; COA_CT_N. 
Pfam
 PF01039; Carboxyl_trans 
SMART
  
PROSITE
 PS50989; COA_CT_CTER
 PS50980; COA_CT_NTER 
PRINTS
 PR01070; ACCCTRFRASEB.