UniProt Accession

 APT1_YEAST; P49435; D6VZF2; Q6Q5A3 

Genbank Protein ID

 U16781; Z46659; AY558232; BK006946 

Genbank Nucleotide ID

 AAA89075.1; CAA86633.1; AAS56558.1; DAA09876.1 

Protein Name

 Adenine phosphoribosyltransferase 1 

Protein Synonyms/Alias

 APRT 1 

Gene Name

 APT1 

Gene Synonyms/Alias

 YML022W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
100	KLPGECFKATYEKEY	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. 

Sequence Annotation

 NP_BIND 133 137 AMP (Probable).
 MOD_RES 68 68 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Glycosyltransferase; Magnesium; Metal-binding; Nucleus; Phosphoprotein; Purine salvage; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 187 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0003999; F:adenine phosphoribosyltransferase activity; IDA:SGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006168; P:adenine salvage; IMP:SGD.
 GO:0006167; P:AMP biosynthetic process; TAS:SGD.
 GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway.
 GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW. 

Interpro

 IPR005764; Ade_phspho_trans.
 IPR000836; PRibTrfase_dom. 

Pfam

 PF00156; Pribosyltran 

SMART

  

PROSITE

 PS00103; PUR_PYR_PR_TRANSFER 

PRINTS