UniProt Accession

 F6PYI8_MOUSE; F6PYI8 

Genbank Protein ID

 AC087064 

Genbank Nucleotide ID

  

Protein Name

 Proline dehydrogenase 1, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Prodh 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
156	NYVLEELKHSTKAEV	acetylation	[1, 2]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 244 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0004657; F:proline dehydrogenase activity; ISS:MGI.
 GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
 GO:0006562; P:proline catabolic process; IEA:InterPro. 

Interpro

 IPR002872; Proline_DH.
 IPR015659; Proline_oxidase. 

Pfam

 PF01619; Pro_dh 

SMART

  

PROSITE

  

PRINTS