CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027131
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aspartate aminotransferase 
Protein Synonyms/Alias
  
Gene Name
 got1 
Gene Synonyms/Alias
 xr406 
Created Date
 July 27, 2013 
Organism
 Xenopus laevis (African clawed frog) 
NCBI Taxa ID
 8355 
Lysine Modification
Position
Peptide
Type
References
274GNLTVVGKDGDNVARacetylation[1]
288RVLSQMEKIVRTTWSacetylation[1]
Reference
 [1] A biotin switch-based proteomics approach identifies 14-3-3ΞΆ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminotransferase; Pyridoxal phosphate; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 411 AA 
Protein Sequence
MASIFCSVPQ APPVAVFKLT ADFRADSDAR KVNLGVGAYR TDDSQPWVLP VVKKVEQMIA 60
NDNSLNHEYL PILGLPEFRS SASRIALGDD SPAFKEDRVG GVQSLGGTGA LRIGAEFLRR 120
WYNGNNNTAT PIYISSPSWE NHNAVFMDAG FKDIRAYRYW DAAKRGLDLE GFLQDLENAP 180
EFSIFLLHAC AHNPTGTDPT PDEWRKIADV MKRRSLFPFF DSAYQGFASG SLDKDAWAVR 240
FFVSQGFELF CAQSFSKNFG LYNERVGNLT VVGKDGDNVA RVLSQMEKIV RTTWSNPPSQ 300
GARIVATTLN TPELFDEWRD NVKTMAERVL LMRAELKSRL EALKTPGTWN HIVNQIGMFS 360
YTGLNPKQVE YLIKEKHIYL MASGRINMCG LTTKNIDYVA QSIYEASTKI Q 411 
Gene Ontology
 GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0009058; P:biosynthetic process; IEA:InterPro.
 GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR000796; Asp_trans.
 IPR004838; NHTrfase_class1_PyrdxlP-BS.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
 PS00105; AA_TRANSFER_CLASS_1 
PRINTS
 PR00799; TRANSAMINASE.