CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031557
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ELL-associated factor 1 
Protein Synonyms/Alias
 cDNA FLJ57288, highly similar to ELL-associated factor 1 
Gene Name
 EAF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
49MPFRAPTKPPVGPKTacetylation[1, 2, 3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 167 AA 
Protein Sequence
MKSQLHCHIS LAEGSSKIQA RMEQQPTRPP QTSQPPPPPP PMPFRAPTKP PVGPKTSPLK 60
DNPSPEPQLD DIKRELRAEV DIIEQMSSSS GSSSSDSESS SGSDDDSSSS GGEDNGPASP 120
PQPSHQQPYN SRPAVANGTS RPQGSNQLMN TLRNDLQLSE SGSDSDD 167 
Gene Ontology
 GO:0032783; C:ELL-EAF complex; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR027093; EAF_fam. 
Pfam
  
SMART
  
PROSITE
  
PRINTS