UniProt Accession

 PTKA_ECOLI; P69828; P37187; P76413; P94757; P97243 

Genbank Protein ID

 X79837; U00096; AP009048; AP009048 

Genbank Nucleotide ID

 CAA56228.1; AAC75155.1; BAA15964.1; BAA15957.2 

Protein Name

 Galactitol-specific phosphotransferase enzyme IIA component 

Protein Synonyms/Alias

 EIIA-Gat; PTS system galactitol-specific EIIA component 

Gene Name

 gatA 

Gene Synonyms/Alias

 b2094; JW2078/JW2081 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
29	IGNEMLAKGVVHDTW	acetylation	[1]
119	LLRCLFGKLQQPDIV	acetylation	[1]
138	TLPETQLKEYFTKYV	acetylation	[1]
143	QLKEYFTKYVLDSDE	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in galactitol transport. 

Sequence Annotation

 DOMAIN 1 144 PTS EIIA type-2.
 ACT_SITE 62 62 Tele-phosphohistidine intermediate (By  

Keyword

 Complete proteome; Cytoplasm; Galactitol metabolism; Kinase; Phosphotransferase system; Reference proteome; Sugar transport; Transferase; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 150 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0005351; F:sugar:hydrogen symporter activity; IEA:InterPro.
 GO:0019402; P:galactitol metabolic process; IEA:UniProtKB-KW.
 GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. 

Interpro

 IPR016152; PTrfase/Anion_transptr.
 IPR002178; PTS_EIIA_2. 

Pfam

 PF00359; PTS_EIIA_2 

SMART

  

PROSITE

 PS51094; PTS_EIIA_TYPE_2 

PRINTS