CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004718
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription regulatory protein SNF6 
Protein Synonyms/Alias
 SWI/SNF complex component SNF6 
Gene Name
 SNF6 
Gene Synonyms/Alias
 YHL025W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
140KSRLFSEKTIRYLMQacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. 
Sequence Annotation
 MOTIF 2 8 Nuclear localization signal (Potential).
 MOD_RES 165 165 Phosphothreonine.  
Keyword
 Activator; Alternative initiation; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 332 AA 
Protein Sequence
MGVIKKKRSH HGKASRQQYY SGVQVGGVGS MGAINNNIPS LTSFAEENNY QYGYSGSSAG 60
MNGRSLTYAQ QQLNKQRQDF ERVRLRPEQL SNIIHDESDT ISFRSNLLKN FISSNDAFNM 120
LSLTTVPCDR IEKSRLFSEK TIRYLMQKQH EMKTQAAELQ EKPLTPLKYT KLIAAAEDGS 180
RSTKDMIDAV FEQDSHLRYQ PDGVVVHRDD PALVGKLRGD LREAPADYWT HAYRDVLAQY 240
HEAKERIRQK EVTAGEAQDE ASLQQQQQQD LQQQQQVVTT VASQSPHATA TEKEPVPAVV 300
DDPLENMFGD YSNEPFNTNF DDEFGDLDAV FF 332 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0016514; C:SWI/SNF complex; IDA:SGD.
 GO:0006338; P:chromatin remodeling; IMP:SGD.
 GO:0006289; P:nucleotide-excision repair; IMP:SGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
 GO:0005987; P:sucrose catabolic process; IMP:SGD.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
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PRINTS