CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011815
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquitin-like protein MDY2 
Protein Synonyms/Alias
 Golgi to ER traffic protein 5; Mating-deficient protein 2; Translation machinery-associated protein 24 
Gene Name
 MDY2 
Gene Synonyms/Alias
 GET5; TMA24; YOL111C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
118ASHISEIKLLLKGKVacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos. 
Sequence Annotation
 DOMAIN 74 152 Ubiquitin-like.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 212 AA 
Protein Sequence
MSTSASGPEH EFVSKFLTLA TLTEPKLPKS YTKPLKDVTN LGVPLPTLKY KYKQNRAKKL 60
KLHQDQQGQD NAAVHLTLKK IQAPKFSIEH DFSPSDTILQ IKQHLISEEK ASHISEIKLL 120
LKGKVLHDNL FLSDLKVTPA NSTITVMIKP NPTISKEPEA EKSTNSPAPA PPQELTVPWD 180
DIEALLKNNF ENDQAAVRQV MERLQKGWSL AK 212 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0072380; C:TRC complex; IDA:SGD.
 GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; IMP:SGD.
 GO:0006620; P:posttranslational protein targeting to membrane; IDA:SGD.
 GO:0045048; P:protein insertion into ER membrane; IGI:SGD. 
Interpro
 IPR000626; Ubiquitin.
 IPR019955; Ubiquitin_supergroup. 
Pfam
 PF00240; ubiquitin 
SMART
 SM00213; UBQ 
PROSITE
 PS00299; UBIQUITIN_1
 PS50053; UBIQUITIN_2 
PRINTS