| Tag | Content |
|---|
| CPLM ID | CPLM-004718 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription regulatory protein SNF6 |
Protein Synonyms/Alias | SWI/SNF complex component SNF6 |
Gene Name | SNF6 |
Gene Synonyms/Alias | YHL025W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 140 | KSRLFSEKTIRYLMQ | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. |
Sequence Annotation | MOTIF 2 8 Nuclear localization signal (Potential).
MOD_RES 165 165 Phosphothreonine. |
Keyword | Activator; Alternative initiation; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 332 AA |
Protein Sequence | MGVIKKKRSH HGKASRQQYY SGVQVGGVGS MGAINNNIPS LTSFAEENNY QYGYSGSSAG 60
MNGRSLTYAQ QQLNKQRQDF ERVRLRPEQL SNIIHDESDT ISFRSNLLKN FISSNDAFNM 120
LSLTTVPCDR IEKSRLFSEK TIRYLMQKQH EMKTQAAELQ EKPLTPLKYT KLIAAAEDGS 180
RSTKDMIDAV FEQDSHLRYQ PDGVVVHRDD PALVGKLRGD LREAPADYWT HAYRDVLAQY 240
HEAKERIRQK EVTAGEAQDE ASLQQQQQQD LQQQQQVVTT VASQSPHATA TEKEPVPAVV 300
DDPLENMFGD YSNEPFNTNF DDEFGDLDAV FF 332 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0016514; C:SWI/SNF complex; IDA:SGD. GO:0006338; P:chromatin remodeling; IMP:SGD. GO:0006289; P:nucleotide-excision repair; IMP:SGD. GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD. GO:0005987; P:sucrose catabolic process; IMP:SGD. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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