CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006617
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trafficking protein particle complex subunit BET3 
Protein Synonyms/Alias
 TRAPP subunit BET3; Transport protein particle 22 kDa subunit 
Gene Name
 BET3 
Gene Synonyms/Alias
 YKR068C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
11TTQSRSLKAMGEEIWubiquitination[1]
85PRCENLVKTSEVLSKubiquitination[1]
185VKLNRILKDEIPIGEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation. Required for sporulation. Has a role late in meiosis following DNA replication. 
Sequence Annotation
 LIPID 80 80 S-palmitoyl cysteine.  
Keyword
 3D-structure; Autophagy; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Lipoprotein; Palmitate; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 193 AA 
Protein Sequence
MVSTTQSRSL KAMGEEIWKN KTEKINTELF TLTYGSIVAQ LCQDYERDFN KVNDHLYSMG 60
YNIGCRLIED FLARTALPRC ENLVKTSEVL SKCAFKIFLN ITPNITNWSH NKDTFSLILD 120
ENPLADFVEL PMDAMKSLWY SNILCGVLKG SLEMVQLDCD VWFVSDILRG DSQTEIKVKL 180
NRILKDEIPI GED 193 
Gene Ontology
 GO:0033106; C:cis-Golgi network membrane; IDA:SGD.
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0000407; C:pre-autophagosomal structure; IEA:UniProtKB-SubCell.
 GO:0030008; C:TRAPP complex; IDA:SGD.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD. 
Interpro
 IPR024096; NO_sig/Golgi_transp_ligand-bd.
 IPR007194; TRAPP_component.
 IPR016721; TRAPP_I_complex_Bet3. 
Pfam
 PF04051; TRAPP 
SMART
  
PROSITE
  
PRINTS