| Tag | Content |
|---|
| CPLM ID | CPLM-010898 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sodium transport ATPase 2 |
Protein Synonyms/Alias | |
Gene Name | ENA2 |
Gene Synonyms/Alias | PMR2B; YDR039C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 47 | DESLRRLKAVGENTL | ubiquitination | [1] | | 750 | EALHRRKKFCAMTGD | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of sodium or lithiums ions to allow salt tolerance. |
Sequence Annotation | ACT_SITE 369 369 4-aspartylphosphate intermediate (By |
Keyword | ATP-binding; Cell membrane; Complete proteome; Hydrolase; Ion transport; Magnesium; Membrane; Nucleotide-binding; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1091 AA |
Protein Sequence | MSEGTVKENN NEEFNAYHTL TTEEAAEFIG TSLTEGLTQD ESLRRLKAVG ENTLGDDTKI 60
DYKAMVLHQV CNAMIMVLVI SMAISFAVRD WITGGVISFV IAVNVLIGLV QEYKATKTMN 120
SLKNLSSPNA HVIRNGKSET INSKDVVPGD ICLVKVGDTI PADLRLIETK NFDTDESLLT 180
GESLPVSKDA NLVFGKEEET SVGDRLNLAF SSSAVVKGRA KGIVIKTALN SEIGKIAKSL 240
QGDSGLISRD PSKSWLQNTW ISTKKVTGAF LGTNVGTPLH RKLSKLAVLL FWIAVLFAII 300
VMASQKFDVD KRVAIYAICV ALSMIPSSLV VVLTITMSVG AAVMVSRNVI VRKLDSLEAL 360
GAVNDICSDK TGTLTQGKML ARQIWIPRFG TITISNSDDP FNPNEGNVSL IPRFSPYEYS 420
HNEDGDVGIL QNFKDRLYEK DLPEDIDMDL FQKWLETATL ANIATVFKDD ATDCWKAHGD 480
PTEIAIQVFA TKMDLPHNAL TGEKSTNQSN ENDQSSLSQH NEKPGSAQFE HIAEFPFDST 540
VKRMSSVYYN NHNETYNIYG KGAFESIISC CSSWYGKDGV KITPLTDCDV ETIRKNVYSL 600
SNEGLRVLGF ASKSFTKDQV NDDQLKNITS NRATAESDLV FLGLIGIYDP PRNETAGAVK 660
KFHQAGINVH MLTGDFVGTA KAIAQEVGIL PTNLYHYSQE IVDSMVMTGS QFDGLSEEEV 720
DDLPVLPLVI ARCSPQTKVR MIEALHRRKK FCAMTGDGVN DSPSLKMANV GIAMGINGSD 780
VSKEASDIVL SDDNFASILN AVEEGRRMTD NIQKFVLQLL AENVAQALYL IIGLVFRDEN 840
GKSVFPLSPV EVLWIIVVTS CFPAMGLGLE KAAPDLMDRP PHDSEVGIFT WEVIIDTFAY 900
GIIMTGSCMA SFTGSLYGIN SGRLGHDCDG TYNSSCRDVY RSRSAAFATM TWCALILAWE 960
VVDMRRSFFR MHPDTDSPVK EFFRSIWGNQ FLFWSIIFGF VSAFPVVYIP VINDKVFLHK 1020
PIGAEWGLAI AFTIAFWIGA ELYKCGKRRY FKTQRAHNPE NDLESNNKRD PFEAYSTSTT 1080
IHTEVNIGIK Q 1091 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0005739; C:mitochondrion; IDA:SGD. GO:0005886; C:plasma membrane; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0046872; F:metal ion binding; IEA:InterPro. GO:0008556; F:potassium-transporting ATPase activity; IMP:SGD. GO:0008554; F:sodium-exporting ATPase activity, phosphorylative mechanism; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |