CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027286
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0531 protein 
Protein Synonyms/Alias
  
Gene Name
 Kif5c 
Gene Synonyms/Alias
 mKIAA0531 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
130KTHTMEGKLHDPQLMubiquitination[1]
198KNRVPYVKGCTERFVubiquitination[1]
258TEKKLSGKLYLVDLAubiquitination[1]
269VDLAGSEKVSKTGAEubiquitination[1]
272AGSEKVSKTGAEGAVubiquitination[1]
284GAVLDEAKNINKSLSubiquitination[1]
416EDEQISAKDQKSLEPubiquitination[1]
444VDGISAEKEKYDEEIubiquitination[1]
446GISAEKEKYDEEITSubiquitination[1]
476SQLAEKLKQQMLDQDubiquitination[1]
683YMQNMEQKRRQLEESubiquitination[1]
700SLSEELAKLRAQEKMubiquitination[1]
796EDQEREVKLEKLLLLubiquitination[1]
799EREVKLEKLLLLNDKubiquitination[1]
806KLLLLNDKREQAREDubiquitination[1]
863GSAAQKQKISFLENNubiquitination[1]
876NNLEQLTKVHKQLVRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 987 AA 
Protein Sequence
QRAAVGSRPP RWRCPAGPPT PSLCPLLLRP EMADPAECSI KVMCRFRPLN EAEILRGDKF 60
IPKFKGEETV VIGQGKPYVF DRVLPPNTTQ EQVYNACAKQ IVKDVLEGYN GTIFAYGQTS 120
SGKTHTMEGK LHDPQLMGII PRIAHDIFDH IYSMDENLEF HIKVSYFEIY LDKIRDLLDV 180
SKTNLAVHED KNRVPYVKGC TERFVSSPEE VMDVIDEGKA NRHVAVTNMN EHSSRSHSIF 240
LINIKQENVE TEKKLSGKLY LVDLAGSEKV SKTGAEGAVL DEAKNINKSL SALGNVISAL 300
AEGTKTHVPY RDSKMTRILQ DSLGGNCRTT IVICCSPSVF NEAETKSTLM FGQRAKTIKN 360
TVSVNLELTA EEWKKKYEKE KEKNKALKSV LQHLEMELNR WRNGEAVPED EQISAKDQKS 420
LEPCDNTPII DNITPVVDGI SAEKEKYDEE ITSLYRQLDD KDDEINQQSQ LAEKLKQQML 480
DQDELLASTR RDYEKIQEEL TRLQIENEAA KDEVKEVLQA LEELAVNYDQ KSQEVEDKTR 540
ANEQLTDELA QKTTTLTTTQ RELSQLQELS NHQKKRATEI LNLLLKDLGE IGGIIGTNDV 600
KTLADVNGVI EEEFTMARLY ISKMKSEVKS LVNRSKQLES AQMDSNRKMN ASERELAACQ 660
LLISQHEAKI KSLTDYMQNM EQKRRQLEES QDSLSEELAK LRAQEKMHEV SFQDKEKEHL 720
TRLQDAEEVK KALEQQMESH REAHQKQLSR LRDEIEEKQR IIDEIRDLNQ KLQLEQERLS 780
SDYNKLKIED QEREVKLEKL LLLNDKREQA REDLKGLEET VSRELQTLHN LRKLFVQDLT 840
TRVKKSVELD SDDGGGSAAQ KQKISFLENN LEQLTKVHKQ LVRDNADLRC ELPKLEKRLR 900
ATAERVKALE SALKEAKENA MRDRKRYQQE VDRIKEAVRA KNMARRAHSA QIAKPIRPGH 960
YPASSPTAVH AVRGGGGGSS NSTHYQK 987 
Gene Ontology
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.