CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Abca8b 
Protein Synonyms/Alias
  
Gene Name
 Abca8 
Gene Synonyms/Alias
 Abca8b 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
494EYKGKPSKIEALKDLacetylation[1]
1570QAFFKLEKVKQTFDLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1621 AA 
Protein Sequence
MIKREISVRQ QTCALLQKNL LKKWRLRRET LMEWMSSLLL LLFLCWYPHG HEATDFSSVP 60
TKDLGRVDSF TQSGFMIGYT PVTSTTRQIM EKVAAVPFMA GRKVLGLLDE ENIRELTESH 120
QEVIRVIFSD TFSYHLKFQF GQRIPKSREH GDHEAHCFEM YEDVDCLISI FWKKGFVALQ 180
AAINAAIIET TTNHSVMEKL LSVSGKFMKI HPFVRQEGIL TDFFIFTCIV SFSPITYFVS 240
ISVARERKKM KGLMMMMGLR DSAFWLSWGL LYAGFVFVMA LSLALVIKSV QFLILTSFTV 300
VFSLFLLYGL SMISLAFLMS VLVRKSVLTG LTVFLLTIFW GSLGFTALYR YLPAPLEWTL 360
SLFSPFAFTL GMAQLLRVDY DLNSNAPPDP AGSSNLIAAT NFMLAFDALL YLALTMYFEK 420
VLPNEYGHQR SPLFFLKPSF WVQPRKPAHV ILEDGIDPAP LSGGSFEPVS PEFHGKESIR 480
IRNISKEYKG KPSKIEALKD LTLDIYEGQI TALLGHSGAG KSTLLNILSG LSVPTKGSVT 540
IYNNRLSEMA DLESVFRISG VCPQSNVQFD FLTVRENLRL FAKIRGVPPQ EVEKEVQRVL 600
LELEMKNIQD ILARNLSGGQ KRKLTFGTAI LGDSQIFLLD EPTAGLDPFS RHRVWNLLKE 660
RKADRVVLFS TQFMDEADIL ADRKVFISRG KLKCAGSSLF LKKKWGVGYH LSLQLKEVCV 720
PENITSLVKQ HIPEAKLSAE RERTLVYTLP LETTYRFPEL CQSLDSCPGL GIDSYGVSMT 780
TLNEVFLKLE GKSAIEEPEV DIVGEGQTER SGDTERLMEM EQTLSTLTET KKKTGSLALW 840
RQQTCAIAKA RLLKLKHERK TLLSVLLVLG VALCPLLFES IKMKILQSAY TWDLSPHSYF 900
LAPGQQPHGM LTQLLIINKT EASIDDFIQS VERQNIALEV DASGARDGTD DPSFNGALTV 960
SGGEKKLHQV SKASAGFFFA SWTSFIDMIN NSCLCISLKG AAVATMNTTF CWDEITNPLQ 1020
QLGKTTFWLT LTSACPPYIA MSSVTDYKNK VWFQLRVSGL FPSAYWFGQA LVDIPLYCFV 1080
FLFMSLMDYL LGFPDATLIV ITHVLQIPCS VGYAISLIFL TYVISFISRK GKKNSGIWSL 1140
CFYIITMFSV VAMLLDFNVD AILYCIIFLL PPSTLIGCLI LSMHLFIYRI SREESIVEPF 1200
LVFLIPLLHV FIFIFTLRCL EWKFGKKTMR KDPIFRISPR NNDVHQNPEE PEGEDEDVQM 1260
ERMRTASALA STSFDEKPVI VASCLRKEYA GKWKHCLSKK KAKIATRNVS FCVRKGEILG 1320
LLGHNGAGKS TSLKMISGDT KSTAGQVLLK GSREGDALGF LGYCPQENAL WPNLTVKEHL 1380
EVFATVLGLS KSHAAVTITR LADALQLQDQ LKSPVKTLSE GVKRKLCFVL SILGNPSILL 1440
LDEPSTGLDP EGQQQIWQAI RAIIKNTDRG ALLTTHYMAE AEALCDRVAI LVSGRLRCIG 1500
SIQHLKSKFG KDYLLEMKVK TLEQVELLNT EVLRLFPQAA RQERYSPLMV YKLPVEDVQP 1560
LSQAFFKLEK VKQTFDLEEY SLSQSTLEQV FLELSKEQEM DGFEEELDSS IKWKLLPQEE 1620
V 1621 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS