CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027505
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aspartate aminotransferase 
Protein Synonyms/Alias
  
Gene Name
 Got2 
Gene Synonyms/Alias
 Got2-RB; Dmel_CG4233 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
310ARVMSQVKILIRGLYacetylation[1]
343DLRAQWLKDVKLMADacetylation[1]
397EQVQKLIKDHSVYLTacetylation[1]
428YLAESIHKVTK****acetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminotransferase; Complete proteome; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MSRTIIMTLK DIVHVWSNDP GERMCRANRV STWFSEVQMG PPDAILGVTE AFKKDTNPKK 60
INLGAGAYRD DNTQPFVLPS VREAEKRVVS RSLDKEYATI IGIPEFYNKA IELALGKGSK 120
RLAAKHNVTA QSISGTGALR IGAAFLAKFW QGNREIYIPS PSWGNHVAIF EHAGLPVNRY 180
RYYDKDTCAL DFGGLIEDLK KIPEKSIVLL HACAHNPTGV DPTLEQWREI SALVKKRNLY 240
PFIDMAYQGF ATGDIDRDAQ AVRTFEADGH DFCLAQSFAK NMGLYGERAG AFTVLCSDEE 300
EAARVMSQVK ILIRGLYSNP PVHGARIAAE ILNNEDLRAQ WLKDVKLMAD RIIDVRTKLK 360
DNLIKLGSSQ NWDHIVNQIG MFCFTGLKPE QVQKLIKDHS VYLTNDGRVS MAGVTSKNVE 420
YLAESIHKVT K 431 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005739; C:mitochondrion; IDA:FlyBase.
 GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IDA:FlyBase.
 GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0006537; P:glutamate biosynthetic process; IDA:FlyBase.
 GO:0045213; P:neurotransmitter receptor metabolic process; IMP:FlyBase.
 GO:0007416; P:synapse assembly; IMP:FlyBase. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR000796; Asp_trans.
 IPR004838; NHTrfase_class1_PyrdxlP-BS.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
 PS00105; AA_TRANSFER_CLASS_1 
PRINTS
 PR00799; TRANSAMINASE.