CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029110
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GRB2-associated binding protein 3, isoform CRA_b 
Protein Synonyms/Alias
 GRB2-associated-binding protein 3; cDNA FLJ44298 fis, clone TRACH2023299, highly similar to Homo sapiens GRB2-associated binding protein 3 (GAB3), mRNA 
Gene Name
 GAB3 
Gene Synonyms/Alias
 hCG_18119 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
356LDNMRTWKADVEGQSubiquitination[1]
537TQALQSTKQEWTDERubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MSAGDAVCTG WLVKSPPERK LQRYAWRKRW FVLRRGRMSG NPDVLEYYRN KHSSKPIRVI 60
DLSECAVWKH VGPSFVRKEF QNNFVFIVKT TSRTFYLVAK TEQEMQVWVH SISQVCNLGH 120
LEDGAADSME SLSYTPSSLQ PSSASSLLTA HAASSSLPRD DPNTNAVATE ETRSESELLF 180
LPDYLVLSNC ETGRLHHTSL PTRCDSWSNS DRSLEQASFD DVFVDCLQPL PSSHLVHPSC 240
HGSGAQEVPS SRPQAALIWS REINGPPRDH LSSSPLLESS LSSTIQVDKN QGSLPCGAKE 300
LDIMSNTPPP RPPKPSHLSE RRQEEWSTHS GSKKPECTLV PRRISLSGLD NMRTWKADVE 360
GQSLRHRDKR LSLNLPCRFS PMYPTASASI EDSYVPMSPQ AGASGLGPHC SPDDYIPMNS 420
GSISSPLPEL PANLEPPPVN RDLKPQRKSR PPPLDLRNLS IIREHASLTR TRTVPCSRTS 480
FLSPERNGIN SARFFANPVS REDEESYIEM KLLLSEEQRV DYVQVDEQKT QALQSTKQEW 540
TDERQSKV 548 
Gene Ontology
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS