CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038591
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 PDZ and LIM domain protein 5 
Protein Synonyms/Alias
  
Gene Name
 Pdlim5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
22GFRLQGGKDFNMPLTubiquitination[1]
34PLTISSLKDGGKASQacetylation[2]
34PLTISSLKDGGKASQubiquitination[1]
89QRASAAAKSEPVSVQacetylation[3]
89QRASAAAKSEPVSVQsuccinylation[3]
89QRASAAAKSEPVSVQubiquitination[1]
97SEPVSVQKPTVTSVCubiquitination[1]
206ESENDNTKKAKEKIPubiquitination[1]
211NTKKAKEKIPLHVFSubiquitination[1]
220PLHVFSPKYTKLRDWacetylation[4]
220PLHVFSPKYTKLRDWubiquitination[1]
223VFSPKYTKLRDWHHEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 239 AA 
Protein Sequence
MSNYSVSLVG PAPWGFRLQG GKDFNMPLTI SSLKDGGKAS QAHVRIGDVV LSIDGISAQG 60
MTHLEAQNKI KACTGSLNMT LQRASAAAKS EPVSVQKPTV TSVCSESAQE LAEGQRRGSQ 120
GDIKQQNGNP GTVKIPPKRP PRKHIVERNT EFYHIPTHSD ASKKRLIEDT EDWRPRTGTT 180
QSRSFRILAQ ITGTEHLTES ENDNTKKAKE KIPLHVFSPK YTKLRDWHHE VSARALNVQ 239 
Gene Ontology
 GO:0030018; C:Z disc; IDA:MGI. 
Interpro
 IPR001478; PDZ. 
Pfam
 PF00595; PDZ 
SMART
 SM00228; PDZ 
PROSITE
 PS50106; PDZ 
PRINTS