CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014003
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein phosphatase 1 regulatory subunit 26 
Protein Synonyms/Alias
  
Gene Name
 PPP1R26 
Gene Synonyms/Alias
 KIAA0649 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
338AQNKGGIKRSASAARacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. 
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Polymorphism; Protein phosphatase inhibitor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1209 AA 
Protein Sequence
MFLMNASPVV ALQSKWEAFG PPGSCRFPRC FSEADEGVES ASVSARVQML ISTLQRDGAA 60
RGTSDERAAQ RGHRAEGCHD ARPAAKPTVH KEPPALAVCG LVADFDPMGE EETTDFGPLV 120
LDSDSDDSVD RDIEEAIQEY LKAKSGAAQP GAGGAQPGAA QPSRAAGGGS RCKPEPAHGS 180
APTALCPPKL VPGSGGGPGS QVGSSKDQGS ASPVSVSSDD SFEQSIRAEI EQFLNEKRQH 240
ETQKCDGSVE KKPDTNENSA KSLLKSHQEP PTKVVHRQGL LGVQKEFAFR KPPRLAKMNV 300
QPRSLRSKVT TTQENEGSTK PATPCRPSEA AQNKGGIKRS ASAARRGKRV MSAAQASEAS 360
DSSSDDGIEE AIQLYQLQKT RKEADGDLPQ RVQLREERAP DPPAHSTSSA TKSALPETHR 420
KTPSKKKLVA TKTMDPGPGG LDTDHAPKLL KETKAPPPAS PASRSEFVER SSCRADTSAE 480
LMCAEAILDI SKTILPAPVE GSDGSLSASP LFYSPNVPSR SDGDSSSVDS DDSIEQEIRT 540
FLALKAQSGS LLARGESCPQ AAQGPLLPPG LNSQTGGHKT PLSKTPDPLL GCKRKRRGGG 600
HVRPSTPKKM QEVVKDGSQD ADHSQGRAEP GHERRDLPIQ GKASEALGGE GTARGPGDTR 660
MSQGQGKTDE ARRLDEKESS EDKSSSLDSD EDLDTAIKDL LRSKRKLKKR CREPRAACRK 720
KVRFSTAQTH FLEQLGGLRR DWKDRGPPVL KSCLSKSKRD SGEGPGKKPP SVFGSTAERM 780
RQEGAASQDA ALAFRVRRPA SASASEGNPF PRESQGPAPS PGSLSDDSSS VDSNDSIELE 840
IRKFLAEKAK ESVSSSEVQA EGPTALGTGG PARPEVLCRK EPAPPPGVCT RSQRARGVPH 900
LAEGLRGTES AGAQGTAGLF SQGGKGLPAA PARGDPVPPR STSGGVSAKG LSVSRRNVYV 960
HKDQSPRGAE PAAKSAFGQL PSCATAGTEA GGARGTFHMG CGSPSFLTPS PGAERDAGAQ 1020
ADRTPPWSDF AHQSRLPSPW VLRSEGRDAV WRGGVGSERD KGSEGPARGL PSLPLAGFSP 1080
LLSTQLFHFG KGVSWGGRQA GLFSPHLGLP LQGPSFSAFR EAQAGPSPVF GSPHLLAKKD 1140
GGPWPTRKAQ AGLSLHDRRS SGSEESILDL RYRRRVNRDD QEQDALGSDA SDFSDTSTED 1200
SGGSSVVKV 1209 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0019902; F:phosphatase binding; IDA:UniProtKB.
 GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
 GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. 
Interpro
 IPR026130; PPP1R26. 
Pfam
  
SMART
  
PROSITE
  
PRINTS