UniProt Accession

 ZA2G_MOUSE; Q64726; Q9DBB7 

Genbank Protein ID

 D21059; AF281658; AY248694; AK005051; BC061646; D44593 

Genbank Nucleotide ID

 BAA04638.1; AAQ14325.1; AAO93093.1; BAB23777.1; AAH61646.1; BAA07996.1 

Protein Name

 Zinc-alpha-2-glycoprotein 

Protein Synonyms/Alias

 Zn-alpha-2-GP; Zn-alpha-2-glycoprotein 

Gene Name

 Azgp1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
160	DPAAANTKLKWEAEK	ubiquitination	[1]
174	KVYVQRAKAYLEEEC	ubiquitination	[1]
186	EECPEMLKRYLNYSR	ubiquitination	[1]
219	PGGNRIFKCLAYGFY	ubiquitination	[1]
236	RISLHWNKANKKLAF	ubiquitination	[1]
240	HWNKANKKLAFEPER	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers (By similarity). 

Sequence Annotation

 DOMAIN 202 287 Ig-like C1-type.
 MOD_RES 18 18 Pyrrolidone carboxylic acid (By
 CARBOHYD 123 123 N-linked (GlcNAc...) (Potential).
 CARBOHYD 190 190 N-linked (GlcNAc...).
 CARBOHYD 254 254 N-linked (GlcNAc...) (Potential).
 DISULFID 118 181 By similarity.
 DISULFID 220 275 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Glycoprotein; Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 307 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0042612; C:MHC class I protein complex; IEA:InterPro.
 GO:0019882; P:antigen processing and presentation; IEA:InterPro.
 GO:0007155; P:cell adhesion; ISS:UniProtKB.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0040014; P:regulation of multicellular organism growth; NAS:UniProtKB. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2. 

Pfam

 PF07654; C1-set
 PF00129; MHC_I 

SMART

  

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS

 PR01638; MHCCLASSI.