UniProt Accession

 TAP26_HUMAN; Q9P031; Q9H2V5; Q9NW62 

Genbank Protein ID

 AF213377; AF161477; BC020647; AK001156 

Genbank Nucleotide ID

 AAG43569.1; AAF29092.1; AAH20647.1; BAA91524.1 

Protein Name

 Thyroid transcription factor 1-associated protein 26 

Protein Synonyms/Alias

 TTF-1-associated protein 26; Coiled-coil domain-containing protein 59; TTF-1-associated protein BR2 

Gene Name

 CCDC59 

Gene Synonyms/Alias

 BR22; TAP26; HSPC128 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
182	EYEQIQAKRAAKKQE	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities. 

Sequence Annotation

  

Keyword

 Complete proteome; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 241 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR009149; BR22.
 IPR013730; rRNA_processing. 

Pfam

 PF08524; rRNA_processing 

SMART

  

PROSITE

  

PRINTS

 PR01854; BR22PROTEIN.