CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043198
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Propionyl-CoA carboxylase alpha chain, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Pcca 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
34VIRPDVAKWELSVKLacetylation[1, 2, 3]
34VIRPDVAKWELSVKLsuccinylation[2]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 166 AA 
Protein Sequence
LLAIASSVFV ASQLRAQRFQ EHSRVPVIRP DVAKWELSVK LHDEDHTVVA SNNGPAFTVE 60
VDGSKLNVTS TWNLASPLLS VNVDGTQRTV QCLSREAGGN MSIQFLGTVY KVHILTKLAA 120
ELNKFMLEKV PKDTSSTLCS PMPGVVVAVS VKPGDMMPGE MSQERP 166 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004658; F:propionyl-CoA carboxylase activity; IMP:MGI.
 GO:0019836; P:hemolysis by symbiont of host erythrocytes; IEA:InterPro. 
Interpro
 IPR003189; SLT_beta. 
Pfam
 PF02258; SLT_beta 
SMART
  
PROSITE
  
PRINTS