CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010008
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Phosphomannomutase 
Protein Synonyms/Alias
 PMM 
Gene Name
 manB 
Gene Synonyms/Alias
 cpsG; MPN_066; MP088 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
519RISGTEPKLKLYFNLacetylation[1]
535NGYLAALKHEAKKMHacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
  
Sequence Annotation
 ACT_SITE 149 149 Phosphoserine intermediate (By
 METAL 149 149 Magnesium; via phosphate group (By
 METAL 301 301 Magnesium (By similarity).
 METAL 303 303 Magnesium (By similarity).
 METAL 305 305 Magnesium (By similarity).  
Keyword
 Complete proteome; Isomerase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 554 AA 
Protein Sequence
MNSNAYLEAQ RWLSHPRVKP NLKEVITAMS AEEIEHFFSL KKPSFGTAGV RGKMAPGYHG 60
MNVFSYAYLT QGYVNYIQSL NPTKKPLRFL VARDTRKHGA LFNGIVCDVI TSMGHVVYMF 120
DNNEPTPTPL VSYVIKKYHF DGGVNVTASH NPKTDNGFKI YDGHGAQLLD FQTDQLIAML 180
PPVVTMLDFE PRGNNELLHF LDNEVVYKNY FDDLKESLVV DNDSFKNLPV VFTGLHGTSV 240
KLLPRFLTYL GYSNIISVQP QNVFDANFAN ADHLNPESKD TWELARQYAS NTKAKLMMAI 300
DPDADRFAIA EWNPQTQDWH YFSGNESGVM VAYYKLKHKQ FKRQPYIVTT VVSTDLVDKI 360
AKKYGAFVKR TNVGFKFIGQ AVNHFSKDNE LVVAFEEAIG MMASDGLNRE KDSFQAAAIM 420
LEIARYCHNK GISLLEFYRG EIFGEFGDYY NWTVPHTIHG VNWKEKMEQV LHQLTTATIK 480
EVVGHKITKI KNYVDINLVE YVLENGNWIK FRISGTEPKL KLYFNLSNGY LAALKHEAKK 540
MHEFLVRLLN LDKA 554 
Gene Ontology
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004615; F:phosphomannomutase activity; IEA:EC.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR005844; A-D-PHexomutase_a/b/a-I.
 IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
 IPR005845; A-D-PHexomutase_a/b/a-II.
 IPR005846; A-D-PHexomutase_a/b/a-III.
 IPR005843; A-D-PHexomutase_C.
 IPR016066; A-D-PHexomutase_CS. 
Pfam
 PF02878; PGM_PMM_I
 PF02879; PGM_PMM_II
 PF02880; PGM_PMM_III
 PF00408; PGM_PMM_IV 
SMART
  
PROSITE
 PS00710; PGM_PMM 
PRINTS